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Heart failure and cardiomyopathies
Review
Role of cardiovascular imaging for the diagnosis and prognosis of cardiac amyloidosis
  1. Ali M Agha1,
  2. Purvi Parwani2,
  3. Avirup Guha3,
  4. Jean B Durand4,
  5. Cezar A Iliescu4,
  6. Saamir Hassan4,
  7. Nicolas L Palaskas4,
  8. Greg Gladish5,
  9. Peter Y Kim4 and
  10. Juan Lopez-Mattei4,5
  1. 1 Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA
  2. 2 Department of Cardiology, Loma Linda University Medical Center, Loma Linda, California, USA
  3. 3 Division of Cardiovascular Medicine, Ohio State University, Columbus, Ohio, USA
  4. 4 Cardiology Department, Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
  5. 5 Diagnostic Radiology Department, Division of Diagnostic Imaging, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
  1. Correspondence to Dr Juan Lopez-Mattei; jlopez9{at}mdanderson.org

Abstract

Cardiac amyloidosis (CA) describes the pathological process of amyloid protein deposition in the extracellular space of the myocardium. Unfortunately, the diagnosis of CA is often made late and when the disease process is advanced. However, advances in cardiovascular imaging have allowed for better prognostication and establishing diagnostic pathways with high sensitivity and specificity. This review discusses the role of echocardiography, cardiac MRI and nuclear cardiology in current clinical practice for diagnosis and prognosis of CA.

  • cardiac amyloidosis
  • global longitudinal strain
  • cardiomyopathy restrictive
  • cardiac mri
  • cardio-oncology

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

https://doi.org/10.1136/openhrt-2018-000881

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    Footnotes

    • Contributors JL-M planned the manuscript. JL-M, AMA and PP developed the manuscript. JL-M, SH, AMA, PP, AG, CAI, PYK, JBD, NLP and GG helped draft the manuscript. JL-M submitted the manuscript and is responsible as guarantor.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent Not required.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Data sharing statement No additional data are available.

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