Top cited articles

To celebrate another year of high quality, cutting edge content published in Open Heart, we have shortlisted the most cited papers of the past 2 years. 


Association of moderately elevated trimethylamine N-oxide with cardiovascular risk: is TMAO serving as a marker for hepatic insulin resistance
DiNicolantonio, James J.; McCarty, Mark; OKeefe, James 10.1136/openhrt-2018-000890

‘Big issues’ in neurodevelopment for children and adults with congenital heart disease Verrall, Charlotte E.; Blue, Gillian M.; Loughran-Fowlds, Alison; Kasparian, Nadine, et al.

Intracoronary near-infrared spectroscopy and the risk of future cardiovascular events Karlsson, Sofia; Anesater, Erik; Fransson, Klara; Andell, Pontus,  et al.

Impella versus IABP in acute myocardial infarction complicated by cardiogenic shock Alushi, Brunilda; Douedari, Andel; Froehlig, Georg; Knie, Wulf,  et al.

Real-world comparison of clopidogrel, prasugrel and ticagrelor in patients undergoing primary percutaneous coronary intervention
Krishnamurthy, Arvindra; Keeble, Claire; Anderson, Michelle; Somers, Kathryn, et al. 10.1136/openhrt-2018-000951

Association of income and health-related quality of life in atrial fibrillation
Guhl, Emily; Althouse, Andrew; Sharbaugh, Michael; Pusateri, Alexandra, et al.

Comparative effectiveness of ACE inhibitors and angiotensin receptor blockers in patients with prior myocardial infarction
Ko, Dennis; Azizi, Paymon; Koh, Maria; Chong, Alice; Austin, Peter, et al.

Standardising practice in cardiology: reducing clinical variation and cost at Ochsner Health System
Oravetz, Phil; White, Christopher J.; Carmouche, David, et al.

Stroke-independent contribution of atrial fibrillation to dementia: a meta-analysis
Saglietto, Andrea; Matta, Mario; Gaita, Fiorenzo; Jacobs, Victoria; Bunch, et al.

Non-steroidal anti-inflammatory drug use in acute myopericarditis: 12-month clinical follow-up
Berg, Jan; Lovrinovic, Marina; Baltensperger, Nora; Kissel, Christine K.; Kottwitz, Jan; Manka, Robert; Patriki, Dimitri; Scherff, Frank; Schmied, Christian, et al.


Direct oral anticoagulants versus warfarin: is new always better than the old?
Burn, John; Pirmohamed, Munir

Optimal antiplatelet strategy after transcatheter aortic valve implantation: a meta-analysis
Ahmad, Yousif; Demir, Ozan; Rajkumar, Christopher; Howard, James P, et al.

Impact of nutritional indices on mortality in patients with heart failure
Yoshihisa, Akiomi; Kanno, Yuki; Watanabe, Shunsuke; Yokokawa, Tetsuro, et al.

Effectiveness of pharmacist’s intervention in the management of cardiovascular diseases
Omboni, Stefano; Caserini, Marina

Major adverse cardiac and cerebrovascular event and patients’ quality of life after endoscopic vein harvesting as compared with open vein harvest (MAQEH): a pilot study
Luckraz, Heyman; Cartwright, Carly; Nagarajan, Kumaresan; Kaur, Prabhjeet, et al.

Cardioprotection by an anti-MASP-2 antibody in a murine model of myocardial infarction
James, E. Clark; Dudler, Thomas; Michael, S. Marber,  et al.

MicroRNA 8059 as a marker for the presence and extent of coronary artery calcification
Senapati, Alpana; Isma’eel, Hussain A.; Kumar, Arnav; Ayache, Ayman, et al.

Disparity in spatial distribution of pericardial calcifications in constrictive pericarditis
Hodges, Gethin W.; Bang, Casper N.; Eugen-Olsen, Jesper,et al.

SuPAR predicts postoperative complications and mortality in patients with asymptomatic aortic stenosis
Kurt; Ray, Simon; Kesaniemi, Antero Y.; Jeppesen, Jorgen L.; Wachtell, Kristian

Prognostic significance of repeated brain natriuretic peptide measurements after percutaneous transluminal septal myocardial ablation in patients with drug-refractory hypertrophic obstructive cardiomyopathy
Akita, Keitaro; Tsuruta, Hikaru; Yuasa, Shinsuke; Murata, Mitsushige, et al.