Diagnostic prediction models for suspected pulmonary embolism: systematic review and independent external validation in primary care

JMT Hendriksen, GJ Geersing, WAM Lucassen… - Bmj, 2015 - bmj.com
Objective To validate all diagnostic prediction models for ruling out pulmonary embolism that
are easily applicable in primary care. Design Systematic review followed by independent …

[HTML][HTML] Impact of polypharmacy and P-glycoprotein-and CYP3A4-modulating drugs on safety and efficacy of oral anticoagulation therapy in patients with atrial …

RE Harskamp, M Teichert, WAM Lucassen… - … drugs and therapy, 2019 - Springer
Purpose To study whether polypharmacy or drug–drug interactions have differential effect
on safety and efficacy in patients treated with direct oral anticoagulants (DOACs) versus …

Prediction models for atrial fibrillation applicable in the community: a systematic review and meta-analysis

JCL Himmelreich, L Veelers, WAM Lucassen… - EP …, 2020 - academic.oup.com
Aims Atrial fibrillation (AF) is a common arrhythmia associated with an increased stroke risk.
The use of multivariable prediction models could result in more efficient primary AF …

Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study

GJ Geersing, PMG Erkens, WAM Lucassen, HR Büller… - Bmj, 2012 - bmj.com
Objective To validate the use of the Wells clinical decision rule combined with a point of care
D-dimer test to safely exclude pulmonary embolism in primary care. Design Prospective …

Opportunistic screening versus usual care for detection of atrial fibrillation in primary care: cluster randomised controlled trial

SB Uittenbogaart, N Verbiest-van Gurp… - Bmj, 2020 - bmj.com
Objective To investigate whether opportunistic screening in primary care increases the
detection of atrial fibrillation compared with usual care. Design Cluster randomised …

Diagnostic accuracy of a smartphone-operated, single-lead electrocardiography device for detection of rhythm and conduction abnormalities in primary care

JCL Himmelreich, EPM Karregat… - The Annals of Family …, 2019 - Annals Family Med
PURPOSE To validate a smartphone-operated, single-lead electrocardiography (1L-ECG)
device (AliveCor KardiaMobile) with an integrated algorithm for atrial fibrillation (AF) against …

CHARGE-AF in a national routine primary care electronic health records database in the Netherlands: validation for 5-year risk of atrial fibrillation and implications for …

JCL Himmelreich, WAM Lucassen, RE Harskamp… - Open …, 2021 - openheart.bmj.com
Aims To validate a multivariable risk prediction model (Cohorts for Heart and Aging
Research in Genomic Epidemiology model for atrial fibrillation (CHARGE-AF)) for 5-year risk …

Frequent premature atrial contractions are associated with atrial fibrillation, brain ischaemia, and mortality: a systematic review and meta-analysis

JCL Himmelreich, WAM Lucassen, M Heugen… - EP …, 2019 - academic.oup.com
Abstract Aims Premature atrial contractions (PACs) are a common cardiac phenomenon,
traditionally considered to be of little clinical significance. Recent studies, however, suggest …

Burden of atrial high-rate episodes and risk of stroke: a systematic review

SB Uittenbogaart, WAM Lucassen… - EP …, 2018 - academic.oup.com
Aims Atrial fibrillation (AF) patients have increased risk of stroke. In paroxysmal AF, the
combination of duration and frequency of episodes defines AF burden. In patients with …

Chest pain in general practice: a systematic review of prediction rules

RE Harskamp, SC Laeven, JCL Himmelreich… - BMJ open, 2019 - bmjopen.bmj.com
Objective To identify and assess the performance of clinical decision rules (CDR) for chest
pain in general practice. Design Systematic review of diagnostic studies. Data sources …