PCSK9 inhibitors and cardiovascular outcomes

…, A Hassanein, J Friebel, U Rauch-Kröhnert - Expert opinion on …, 2020 - Taylor & Francis
Introduction: Dyslipidemia, particularly elevated low-density lipoprotein cholesterol (LDL-C),
is a key risk factor for atherosclerotic cardiovascular disease (ASCVD), and lipid-lowering …

Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap …

…, G Fröhlich, U Rauch-Kröhnert… - European Heart …, 2020 - academic.oup.com
Aims Acute coronary syndromes with intact fibrous cap (IFC-ACS), ie caused by coronary
plaque erosion, account for approximately one-third of ACS. However, the underlying …

Toll-like receptor 2, hyaluronan, and neutrophils play a key role in plaque erosion: the OPTICO–ACS study

…, C Skurk, A Haghikia, U Rauch-Kröhnert… - European Heart …, 2023 - academic.oup.com
Background and aims In one-third of patients with acute coronary syndrome (ACS),
thrombosis occurs despite an intact fibrous cap (IFC)(IFC–ACS,'plaque erosion'). Recent …

Left-ventricular unloading in extracorporeal cardiopulmonary resuscitation due to acute myocardial infarction–a multicenter study

…, G Girke, A Haghikia, M Reinthaler, U Rauch-Kröhnert… - Resuscitation, 2023 - Elsevier
Background Guidelines advocate the use of extracorporeal cardio-pulmonary resuscitation
with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in selected patients …

Effects of empagliflozin in women and men with heart failure and preserved ejection fraction

…, S Kaul, IL Piña, P Ponikowski, U Rauch-Kröhnert… - Circulation, 2022 - Am Heart Assoc
Background: Women and men with heart failure (HF) and preserved ejection fraction may
differ in their clinical characteristics and their response to therapy. The aim of this study was …

[HTML][HTML] The role of NETosis and complement activation in COVID-19-associated coagulopathies

…, N Kränkel, U Landmesser, U Rauch-Kröhnert - Biomedicines, 2023 - mdpi.com
Inflammation-induced coagulopathy is a common complication associated with coronavirus
disease 2019 (COVID-19). We aim to evaluate the association of NETosis and complement …

Real‐time optical coherence tomography coregistration with angiography in percutaneous coronary intervention–impact on physician decision‐making: The OPTICO …

…, L Lübking, U RauchKröhnert… - Catheterization and …, 2018 - Wiley Online Library
Aims Intracoronary optical coherence tomography (OCT) imaging allows for high‐resolution
characterization of coronary lesions. Difficulties in matching cross‐sectional OCT‐images …

Coexistence of calcified-and lipid-containing plaque components and their association with incidental rupture points in acute coronary syndrome-causing culprit …

…, M Riedel, C Skurk, U Rauch-Kröhnert… - European Heart …, 2022 - academic.oup.com
Aims Rupture of the fibrous cap (RFC) represents the main pathophysiological mechanism
causing acute coronary syndromes (ACS). Destabilization due to plaque biomechanics is …

[HTML][HTML] Initial therapeutic anticoagulation with rivaroxaban compared to prophylactic therapy with heparins in moderate to severe COVID-19: results of the COVID …

U Rauch-Kröhnert, M Puccini, M Placzek… - Clinical Research in …, 2023 - Springer
Background COVID-19 is associated with a prothrombotic state. Current guidelines
recommend prophylactic anticoagulation upon hospitalization. Methods COVID-PREVENT …

Depression, anxiety, and vital exhaustion are associated with pro-coagulant markers in depressed patients with coronary artery disease–A cross sectional and …

HC Deter, K Orth-Gomér, U Rauch-Kröhnert… - Journal of …, 2021 - Elsevier
Introduction A hyper-coagulant state is a biological mechanism that triggers cardiac events
in patients with coronary artery disease (CAD). Depressive symptoms and anxiety predict an …