Platelets play a fundamental role in hemostasis and thrombosis. They are also involved in
pathologic conditions resulting from blocked blood vessels, including myocardial infarction …

During thrombopoiesis, maturing megakaryocytes (MKs) migrate within the complex bone
marrow stromal microenvironment from the proliferative osteoblastic niche to the capillary …

Migration of megakaryocytes (MKs) from the proliferative osteoblastic niche to the capillary-
rich vascular niche is essential for proplatelet formation and platelet release. In this study …

Background Substrate mapping has highlighted the importance of targeting diastolic
conduction channels and late potentials during ventricular tachycardia (VT) ablation. State …

PECAM-1 is a member of the superfamily of immunoglobulins (Ig) and is expressed on
platelets at moderate level. PECAM-1 has been reported to have contrasting effects on …

Radiofrequency catheter ablation has become an established treatment for ventricular
tachycardia. The exponential increase in procedures has provided further insights into …

Predict the Impact of PVC on Myocardial Function Introduction Reversible premature
ventricular complexes‐induced cardiomyopathy (PVC‐CMP) is a well‐described, multi …

Although the expression of PECAM-1 (CD31) on vascular and haematopoietic cells within
the bone marrow microenvironment has been recognized for some time, its physiological …

Background Defining diastolic slow-conduction channels within the borderzone (BZ) of scar-
dependent re-entrant ventricular tachycardia (VT) is key for effective mapping and ablation …

Objectives: In this study the authors determined the extent of cellular infiltration and
dispersion, and regional vascularization in electrophysiologically (EP) defined zones in post …