Background We assessed the relation between the severity of stenosis in a coronary artery
and the degree of impairment of myocardial blood flow. Studies in laboratory animals have …

Background The use of non-invasive imaging to identify ruptured or high-risk coronary
atherosclerotic plaques would represent a major clinical advance for prevention and …

Background The appropriate treatment for patients in whom reperfusion fails to occur after
thrombolytic therapy for acute myocardial infarction remains unclear. There are few data …

Background The ability of the coronary vascular bed to dilate and thus increase blood flow to
the myocardium may be impaired in coronary artery disease, even in regions of myocardium …

Aims To investigate whether intravascular ultrasound provides additional information
regarding the prediction of stent thrombosis, a retrospective multicentre registry was …

Background—We assessed trends in the performance of transcatheter aortic valve
implantation in the United Kingdom from the first case in 2007 to the end of 2012. We …

Background—The aim of the study was to establish the influence of proximal coronary artery
atheroma and smoking habit on the stimulated release of tissue plasminogen activator (tPA) …

Aims To investigate if recent technical and procedural developments in percutaneous
coronary intervention (PCI) significantly influence outcomes in appropriately selected …

Background Many patients with coronary artery disease who are not candidates for
revascularization have refractory angina despite standard medical therapy. The balloon …

METhODS Subjects Fifty-sixnormal subjects (21 women, 35 men; mean age 50 ±20 yr,
range 21— 86yr) were studied. All subjectswere at lowrisk for coronary artery disease …