Noncardiac comorbidities in heart failure with reduced versus preserved ejection fraction

RJ Mentz, JP Kelly, TG von Lueder, AA Voors… - Journal of the American …, 2014 - jacc.org
Heart failure patients are classified by ejection fraction (EF) into distinct groups: heart failure
with preserved ejection fraction (HFpEF) or heart failure with reduced ejection fraction …

Diuretic response in acute heart failure: clinical characteristics and prognostic significance

MAE Valente, AA Voors, K Damman… - European heart …, 2014 - academic.oup.com
Aim Diminished diuretic response is common in patients with acute heart failure, although a
clinically useful definition is lacking. Our aim was to investigate a practical, workable metric …

Depression and heart failure: the lonely comorbidity

M Sbolli, M Fiuzat, D Cani… - European journal of …, 2020 - Wiley Online Library
Depression is a frequent and debilitating comorbidity that affects heart failure (HF) patients.
Up to 30% of HF patients suffer from depression and even more have depressive symptoms …

Universal definition and classification of heart failure: a report of the heart failure society of America, heart failure association of the European society of cardiology …

B Bozkurt, AJS Coats, H Tsutsui, M Abdelhamid… - Journal of cardiac …, 2021 - Elsevier
Summary of Key Points In this document, we propose a universal definition of heart failure
(HF) as the following: HF is a clinical syndrome with symptoms and or signs caused by a …

Palliative care in heart failure: the PAL-HF randomized, controlled clinical trial

JG Rogers, CB Patel, RJ Mentz, BB Granger… - Journal of the American …, 2017 - jacc.org
Background: Advanced heart failure (HF) is characterized by high morbidity and mortality.
Conventional therapy may not sufficiently reduce patient suffering and maximize quality of …

Effect of natriuretic peptide–guided therapy on hospitalization or cardiovascular mortality in high-risk patients with heart failure and reduced ejection fraction: a …

GM Felker, KJ Anstrom, KF Adams, JA Ezekowitz… - Jama, 2017 - jamanetwork.com
Importance The natriuretic peptides are biochemical markers of heart failure (HF) severity
and predictors of adverse outcomes. Smaller studies have evaluated adjusting HF therapy …

Galectin-3 in ambulatory patients with heart failure: results from the HF-ACTION study

GM Felker, M Fiuzat, LK Shaw, R Clare… - Circulation: heart …, 2012 - Am Heart Assoc
Background—Galectin-3 is a soluble ß-galactoside–binding lectin released by activated
cardiac macrophages. Elevated levels of galectin-3 have been found to be associated with …

Triage after hospitalization with advanced heart failure: the ESCAPE (Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization …

CM O'Connor, V Hasselblad, RH Mehta… - Journal of the American …, 2010 - jacc.org
Objectives: Identifying high-risk heart failure (HF) patients at hospital discharge may allow
more effective triage to management strategies. Background: Heart failure severity at …

Clinical implications of the New York heart association classification

C Caraballo, NR Desai, H Mulder… - Journal of the …, 2019 - Am Heart Assoc
Background The New York Heart Association (NYHA) classification has served as a
fundamental tool for risk stratification of heart failure (HF) and determines clinical trial …

Efficacy and safety of tolvaptan in patients hospitalized with acute heart failure

GM Felker, RJ Mentz, RT Cole, KF Adams… - Journal of the American …, 2017 - jacc.org
Background: The oral vasopressin-2 receptor antagonist tolvaptan causes aquaresis in
patients with volume overload, potentially facilitating decongestion and improving the …