Long-term clinical outcomes of losartan in patients with Marfan syndrome: follow-up of the multicentre randomized controlled COMPARE trial
MM van Andel, R Indrakusuma… - European heart …, 2020 - academic.oup.com
Aims The COMPARE trial showed a small but significant beneficial effect of 3-year losartan
treatment on aortic root dilatation rate in adults with Marfan syndrome (MFS). However, no …
treatment on aortic root dilatation rate in adults with Marfan syndrome (MFS). However, no …
[HTML][HTML] The potential beneficial effects of resveratrol on cardiovascular complications in Marfan syndrome patients–insights from rodent-based animal studies
MM van Andel, M Groenink, AH Zwinderman… - International journal of …, 2019 - mdpi.com
Marfan syndrome (MFS) patients are at risk for cardiovascular disease. In particular, for
aortic aneurysm formation, which ultimately can result in a life-threatening aortic dissection …
aortic aneurysm formation, which ultimately can result in a life-threatening aortic dissection …
[HTML][HTML] Genome-wide methylation patterns in Marfan syndrome
MM van Andel, M Groenink, MP van den Berg… - Clinical …, 2021 - Springer
Background Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in
the Fibrillin-1 gene (FBN1). Here, we undertook the first epigenome-wide association study …
the Fibrillin-1 gene (FBN1). Here, we undertook the first epigenome-wide association study …
Aortic distensibility in Marfan syndrome: a potential predictor of aortic events?
MM van Andel, V de Waard, J Timmermans… - Open …, 2021 - openheart.bmj.com
Objectives Patients with Marfan syndrome (MFS) are prone to develop aortic aneurysms due
to fragmentation of elastic fibres, resulting in reduced distensibility of the aorta. Reduced …
to fragmentation of elastic fibres, resulting in reduced distensibility of the aorta. Reduced …
A cross‐sectional study on fatigue, anxiety, and symptoms of depression and their relation with medical status in adult patients with M arfan syndrome. Psychological …
MM van Andel, K Graaumans, M Groenink… - Clinical …, 2022 - Wiley Online Library
Marfan syndrome (MFS) is a connective tissue disorder affecting the cardiovascular, ocular,
and skeletal system, which may be accompanied by psychological features. This study …
and skeletal system, which may be accompanied by psychological features. This study …
[HTML][HTML] Abnormal aortic hemodynamics are associated with risk factors for aortic complications in patients with marfan syndrome
MM van Andel, P van Ooij, V de Waard… - IJC Heart & …, 2022 - Elsevier
Background It is difficult to assess the risk for aortic dissection beyond the aortic root in
patients with Marfan syndrome (MFS). To aid risk assessment in these patients, we …
patients with Marfan syndrome (MFS). To aid risk assessment in these patients, we …
The Effect of Resveratrol on Aortic Function in Patients with Marfan Syndrome–Rationale and Design of the Resvcue Marfan Trial.
MM van Andel, P van Ooij, AJHA Scholte… - 2021 - researchsquare.com
Background Marfan syndrome (MFS) is a connective tissue disorder characterized by
mutations in the fibrillin-1 (FBN1) gene. The most important manifestation is progressive …
mutations in the fibrillin-1 (FBN1) gene. The most important manifestation is progressive …
Marfan syndrome: The complex road to an optimal treatment strategy
MM van Andel - 2023 - researchinformation.amsterdamumc …
Marfan syndrome (MFS) is a heritable connective tissue disorder affecting the ocular,
skeletal and cardiovascular system. The management of patients with MFS requires a …
skeletal and cardiovascular system. The management of patients with MFS requires a …