Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised …

N Sattar, MMY Lee, SL Kristensen… - The lancet Diabetes & …, 2021 - thelancet.com
Background GLP-1 receptor agonists reduce major adverse cardiovascular events (MACE)
in patients with type 2 diabetes. However, uncertainty regarding kidney outcomes persists …

[HTML][HTML] Statins in the prevention and treatment of heart failure: a review of the evidence

MMY Lee, N Sattar, JJV McMurray… - Current atherosclerosis …, 2019 - Springer
Abstract Purpose of Review We summarize the best evidence for statins in the prevention
and treatment of heart failure. Recent Findings In patients with cardiovascular risk factors or …

Effect of empagliflozin on left ventricular volumes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF)

MMY Lee, KJM Brooksbank, K Wetherall, K Mangion… - Circulation, 2021 - Am Heart Assoc
Background: Sodium-glucose cotransporter 2 inhibitors reduce the risk of heart failure
hospitalization and cardiovascular death in patients with heart failure and reduced ejection …

Meta-analyses of results from randomized outcome trials comparing cardiovascular effects of SGLT2is and GLP-1RAs in Asian versus white patients with and without …

MMY Lee, N Ghouri, DK McGuire, MK Rutter… - Diabetes …, 2021 - Am Diabetes Assoc
BACKGROUND Results of cardiovascular outcome trials (CVOTs) suggest Asians may
derive greater benefit than Whites from newer classes of antihyperglycemic medications …

Reducing personal exposure to particulate air pollution improves cardiovascular health in patients with coronary heart disease

JP Langrish, X Li, S Wang, MMY Lee… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Air pollution exposure increases cardiovascular morbidity and mortality and is
a major global public health concern. Objectives: We investigated the benefits of reducing …

Fractional flow reserve vs. angiography in guiding management to optimize outcomes in non-ST-segment elevation myocardial infarction: the British Heart Foundation …

J Layland, KG Oldroyd, N Curzen, A Sood… - European heart …, 2015 - academic.oup.com
Aim We assessed the management and outcomes of non-ST segment elevation myocardial
infarction (NSTEMI) patients randomly assigned to fractional flow reserve (FFR)-guided …

Lung ultrasound in acute heart failure: prevalence of pulmonary congestion and short-and long-term outcomes

E Platz, RT Campbell, B Claggett, EF Lewis… - JACC: Heart Failure, 2019 - jacc.org
Objectives: This study sought to assess the prevalence, changes in, and prognostic
importance of B-lines, a pulmonary congestion measure by using a simplified lung …

Effect of neprilysin inhibition on left ventricular remodeling in patients with asymptomatic left ventricular systolic dysfunction late after myocardial infarction

KF Docherty, RT Campbell, KJM Brooksbank… - Circulation, 2021 - Am Heart Assoc
Background: Patients with left ventricular (LV) systolic dysfunction after myocardial infarction
are at a high risk of developing heart failure. The addition of neprilysin inhibition to renin …

[HTML][HTML] Prevalence of prediabetes and undiagnosed diabetes in patients with HFpEF and HFrEF and associated clinical outcomes

SL Kristensen, PS Jhund, MMY Lee, L Køber… - … drugs and therapy, 2017 - Springer
Purpose The prevalence and consequences of prediabetic dysglycemia and undiagnosed
diabetes is unknown in patients with heart failure (HF) and preserved ejection fraction …

Renin–angiotensin system blockers, risk of SARS-CoV-2 infection and outcomes from CoViD-19: systematic review and meta-analysis

MMY Lee, KF Docherty, N Sattar… - European Heart …, 2022 - academic.oup.com
Aims This meta-analysis provides summary odds ratio (OR) estimates for associations
between treatment with (vs. without) renin–angiotensin system blockers and risk of severe …