Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials …

D Keene, C Price, MJ Shun-Shin, DP Francis - Bmj, 2014 - bmj.com
Objective To investigate the effects on cardiovascular outcomes of drug interventions that
increase high density lipoprotein levels. Design Meta-analysis. Studies reviewed …

Association between use of sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide 1 agonists, and dipeptidyl peptidase 4 inhibitors with all-cause mortality …

SL Zheng, AJ Roddick, R Aghar-Jaffar, MJ Shun-Shin… - Jama, 2018 - jamanetwork.com
Importance The comparative clinical efficacy of sodium-glucose cotransporter 2 (SGLT-2)
inhibitors, glucagon-like peptide 1 (GLP-1) agonists, and dipeptidyl peptidase 4 (DPP-4) …

Discrepancies in autologous bone marrow stem cell trials and enhancement of ejection fraction (DAMASCENE): weighted regression and meta-analysis

AN Nowbar, M Mielewczik, M Karavassilis, HM Dehbi… - Bmj, 2014 - bmj.com
Objective To investigate whether discrepancies in trials of use of bone marrow stem cells in
patients with heart disease account for the variation in reported effect size in improvement of …

[HTML][HTML] N-of-1 trial of a statin, placebo, or no treatment to assess side effects

FA Wood, JP Howard, JA Finegold… - … England Journal of …, 2020 - Mass Medical Soc
N-of-1 Trial of a Statin, Placebo, or No Treatment Patients who had discontinued statins
because of side effects received four bottles of a statin, four bottles of placebo, and four …

A placebo-controlled trial of percutaneous coronary intervention for stable angina

CA Rajkumar, MJ Foley, F Ahmed-Jushuf… - … England Journal of …, 2023 - Mass Medical Soc
Background Percutaneous coronary intervention (PCI) is frequently performed to reduce the
symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in …

Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis

MA Kelshiker, H Seligman, JP Howard… - European heart …, 2022 - academic.oup.com
Aims This meta-analysis aims to quantify the association of reduced coronary flow with all-
cause mortality and major adverse cardiovascular events (MACE) across a broad range of …

His resynchronization versus biventricular pacing in patients with heart failure and left bundle branch block

AD Arnold, MJ Shun-Shin, D Keene, JP Howard… - Journal of the American …, 2018 - jacc.org
Background: His bundle pacing is a new method for delivering cardiac resynchronization
therapy (CRT). Objectives: The authors performed a head-to-head, high-precision, acute …

Side effect patterns in a crossover trial of statin, placebo, and no treatment

JP Howard, FA Wood, JA Finegold, AN Nowbar… - Journal of the American …, 2021 - jacc.org
Background Most people who begin statins abandon them, most commonly because of side
effects. Objectives The purpose of this study was to assess daily symptom scores on statin …

High-throughput precision phenotyping of left ventricular hypertrophy with cardiovascular deep learning

G Duffy, PP Cheng, N Yuan, B He, AC Kwan… - JAMA …, 2022 - jamanetwork.com
Importance Early detection and characterization of increased left ventricular (LV) wall
thickness can markedly impact patient care but is limited by under-recognition of …

Diagnostic accuracy of computed tomography–derived fractional flow reserve: a systematic review

CM Cook, R Petraco, MJ Shun-Shin, Y Ahmad… - JAMA …, 2017 - jamanetwork.com
Importance Computed tomography–derived fractional flow reserve (FFR-CT) is a novel,
noninvasive test for myocardial ischemia. Clinicians using FFR-CT must be able to interpret …