[HTML][HTML] Study designs and statistical analyses for biomarker research
M Gosho, K Nagashima, Y Sato - Sensors, 2012 - mdpi.com
Biomarkers are becoming increasingly important for streamlining drug discovery and
development. In addition, biomarkers are widely expected to be used as a tool for disease …
development. In addition, biomarkers are widely expected to be used as a tool for disease …
Vitamin E has a beneficial effect on nonalcoholic fatty liver disease: a meta-analysis of randomized controlled trials
K Sato, M Gosho, T Yamamoto, Y Kobayashi, N Ishii… - Nutrition, 2015 - Elsevier
Objectives Vitamin E is often used in the treatment of nonalcoholic fatty liver disease
(NAFLD), including nonalcoholic steatohepatitis (NASH); however, the magnitude of …
(NAFLD), including nonalcoholic steatohepatitis (NASH); however, the magnitude of …
Alogliptin, a dipeptidyl peptidase 4 inhibitor, prevents the progression of carotid atherosclerosis in patients with type 2 diabetes: the study of preventive effects of …
T Mita, N Katakami, H Yoshii, T Onuma… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Recent experimental studies have shown that dipeptidyl peptidase 4 (DPP-4)
inhibitors have antiatherosclerotic benefits in glucagon-like peptide 1–dependent and …
inhibitors have antiatherosclerotic benefits in glucagon-like peptide 1–dependent and …
Sitagliptin attenuates the progression of carotid intima-media thickening in insulin-treated patients with type 2 diabetes: the sitagliptin preventive study of intima-media …
T Mita, N Katakami, T Shiraiwa, H Yoshii… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE The effect of additional treatment with oral hypoglycemic agents on the
progression of atherosclerosis remains unknown in insulin-treated patients with type 2 …
progression of atherosclerosis remains unknown in insulin-treated patients with type 2 …
Prevalence of Helicobacter pylori Infection by Birth Year and Geographic Area in Japan
J Ueda, M Gosho, Y Inui, T Matsuda… - …, 2014 - Wiley Online Library
Background Helicobacter pylori (H. pylori)‐related diseases are responsible for a
tremendous amount of morbidity and mortality in Japan. We estimated the prevalence of H …
tremendous amount of morbidity and mortality in Japan. We estimated the prevalence of H …
A comparison of bias‐adjusted generalized estimating equations for sparse binary data in small‐sample longitudinal studies
Using a generalized estimating equation (GEE) can lead to a bias in regression coefficients
for a small sample or sparse data. The bias‐corrected GEE (BCGEE) and penalized GEE …
for a small sample or sparse data. The bias‐corrected GEE (BCGEE) and penalized GEE …
Propensity score analysis of regorafenib versus trifluridine/tipiracil in patients with metastatic colorectal cancer refractory to standard chemotherapy (REGOTAS): a …
T Moriwaki, S Fukuoka, H Taniguchi… - The …, 2018 - academic.oup.com
Background This study compared the efficacy of regorafenib and trifluridine/tipiracil (TFTD)
in patients with metastatic colorectal cancer (mCRC) who are refractory to standard …
in patients with metastatic colorectal cancer (mCRC) who are refractory to standard …
Bias in odds ratios from logistic regression methods with sparse data sets
Background: Logistic regression models are widely used to evaluate the association
between a binary outcome and a set of covariates. However, when there are few study …
between a binary outcome and a set of covariates. However, when there are few study …
Fluctuations in routine blood count might signal severe immune-related adverse events in melanoma patients treated with nivolumab
Y Fujisawa, K Yoshino, A Otsuka, T Funakoshi… - Journal of …, 2017 - Elsevier
Background Although nivolumab significantly prolongs survival of metastatic melanoma,
about 10% of patients experience severe, even fatal immune-related adverse events (irAEs) …
about 10% of patients experience severe, even fatal immune-related adverse events (irAEs) …
Robot-assisted training as self-training for upper-limb hemiplegia in chronic stroke: a randomized controlled trial
T Takebayashi, K Takahashi, S Amano, M Gosho… - Stroke, 2022 - Am Heart Assoc
Background: This study aimed to examine whether robotic self-training improved upper-
extremity function versus conventional self-training in mild-to-moderate hemiplegic chronic …
extremity function versus conventional self-training in mild-to-moderate hemiplegic chronic …