Objectives Despite vigorous infection control measures, Clostridium difficile continues to
cause significant disease burden. Antibiotic stewardship programmes (ASPs) may prevent …

Objective Polypharmacy has been linked to a myriad of adverse consequences, and
escalating rates of polypharmacy present an emerging concern, particularly among older …

Colonization with health care-associated pathogens such as Staphylococcus aureus,
enterococci, Gram-negative organisms, and Clostridium difficile is associated with increased …

Previously published guidelines provide comprehensive recommendations for hand
hygiene in healthcare facilities. The intent of this document is to highlight practical …

Importance Previous studies suggested that a bundled intervention was associated with
lower rates ofStaphylococcus aureussurgical site infections (SSIs) among patients having …

Background The high prevalence of methicillin-resistant S. aureus (MRSA) has led clinicians
to select antibiotics that have coverage against MRSA, usually vancomycin, for empiric …

Objectives: This study sought to determine the safety and efficacy of radial access compared
with femoral access for primary percutaneous coronary intervention (PCI) in patients with ST …

Background context Some surgeons use systemic vancomycin to prevent surgical site
infections (SSIs), but patients who do not carry methicillin-resistant Staphylococcus aureus …

Objective To evaluate studies assessing the effectiveness of a bundle of nasal
decolonization and glycopeptide prophylaxis for preventing surgical site infections caused …

Quasi-experimental studies evaluate the association between an intervention and an
outcome using experiments in which the intervention is not randomly assigned. Quasi …