The need for a quantitative and operator-independent assessment of coronary
microvascular function is increasingly recognized. We propose the theoretical framework of …

Objectives: The purpose of this study was to investigate the appropriateness of stenting a
functionally nonsignificant stenosis. Background: Percutaneous coronary intervention (PCI) …

Objectives: The purpose of this study was to investigate the 2-year outcome of percutaneous
coronary intervention (PCI) guided by fractional flow reserve (FFR) in patients with …

Objectives: The purpose of this study was to investigate the relationship between
angiographic and functional severity of coronary artery stenoses in the FAME (Fractional …

Summary Background In the Fractional Flow Reserve Versus Angiography for Multivessel
Evaluation (FAME) study, fractional flow reserve (FFR)-guided percutaneous coronary …

Coronary microvascular dysfunction is a highly prevalent condition in both obstructive and
nonobstructive coronary artery disease. Intracoronary thermodilution is a promising …

Objectives: This study sought to examine the diagnostic accuracy of the instantaneous wave-
free ratio (iFR) and resting distal coronary artery pressure/aortic pressure (P d/P a) with …

Objectives: This study sought to compare fractional flow reserve (FFR) with the
instantaneous wave-free ratio (iFR) in patients with coronary artery disease and also to …

Objectives: The aim of this study was to study whether there is a difference in benefit of
fractional flow reserve (FFR) guidance for percutaneous coronary intervention (PCI) in …

Objectives: This study sought to validate a new method for direct volumetric blood flow
measurement in coronary arteries in animals and in conscious humans during cardiac …