User profiles for "author:Lei Clifton"

Lei Clifton

Senior Medical Statistician, University of Oxford
Verified email at ndph.ox.ac.uk
Cited by 4523

A review of novelty detection

MAF Pimentel, DA Clifton, L Clifton, L Tarassenko - Signal processing, 2014 - Elsevier
Novelty detection is the task of classifying test data that differ in some respect from the data
that are available during training. This may be seen as “one-class classification”, in which a …

Predictive monitoring of mobile patients by combining clinical observations with data from wearable sensors

L Clifton, DA Clifton, MAF Pimentel… - IEEE journal of …, 2013 - ieeexplore.ieee.org
The majority of patients in the hospital are ambulatory and would benefit significantly from
predictive and personalized monitoring systems. Such patients are well suited to having …

[HTML][HTML] Efficacy of cognitive behavioural therapy for sleep improvement in patients with persistent delusions and hallucinations (BEST): a prospective, assessor-blind …

D Freeman, F Waite, H Startup, E Myers… - The Lancet …, 2015 - thelancet.com
Background Sleep disturbance occurs in most patients with delusions or hallucinations and
should be treated as a clinical problem in its own right. However, cognitive behavioural …

Multitask Gaussian processes for multivariate physiological time-series analysis

R Dürichen, MAF Pimentel, L Clifton… - IEEE Transactions …, 2014 - ieeexplore.ieee.org
Gaussian process (GP) models are a flexible means of performing nonparametric Bayesian
regression. However, GP models in healthcare are often only used to model a single …

[HTML][HTML] Calculating polygenic risk scores (PRS) in UK Biobank: a practical guide for epidemiologists

JA Collister, X Liu, L Clifton - Frontiers in genetics, 2022 - frontiersin.org
A polygenic risk score estimates the genetic risk of an individual for some disease or trait,
calculated by aggregating the effect of many common variants associated with the condition …

[HTML][HTML] Comparing the efficacy of a mobile phone-based blood glucose management system with standard clinic care in women with gestational diabetes …

L Mackillop, JE Hirst, KJ Bartlett, JS Birks… - JMIR mHealth and …, 2018 - mhealth.jmir.org
Background: Treatment of hyperglycemia in women with gestational diabetes mellitus
(GDM) is associated with improved maternal and neonatal outcomes and requires intensive …

Gaussian processes for personalized e-health monitoring with wearable sensors

L Clifton, DA Clifton, MAF Pimentel… - IEEE Transactions …, 2012 - ieeexplore.ieee.org
Advances in wearable sensing and communications infrastructure have allowed the
widespread development of prototype medical devices for patient monitoring. However …

[HTML][HTML] The correlation between baseline score and post-intervention score, and its implications for statistical analysis

L Clifton, DA Clifton - Trials, 2019 - Springer
Background When using a continuous outcome measure in a randomised controlled trial
(RCT), the baseline score should be measured in addition to the post-intervention score …

Identification of patient deterioration in vital-sign data using one-class support vector machines

L Clifton, DA Clifton, PJ Watkinson… - … on computer science …, 2011 - ieeexplore.ieee.org
Adverse hospital patient outcomes due to deterioration are often preceded by periods of
physiological deterioration that is evident in the vital signs, such as heart rate, respiratory …

[HTML][HTML] A medical multimodal large language model for future pandemics

F Liu, T Zhu, X Wu, B Yang, C You, C Wang, L Lu… - NPJ Digital …, 2023 - nature.com
Deep neural networks have been integrated into the whole clinical decision procedure
which can improve the efficiency of diagnosis and alleviate the heavy workload of …