Multiple arterial grafts improve late survival of patients undergoing coronary artery bypass graft surgery: analysis of 8622 patients with multivessel disease

C Locker, HV Schaff, JA Dearani, LD Joyce, SJ Park… - Circulation, 2012 - Am Heart Assoc
Background—Use of the left internal mammary artery (LIMA) in multivessel coronary artery
disease improves survival after coronary artery bypass graft surgery; however, the survival …

[HTML][HTML] Transcatheter or surgical aortic-valve replacement in intermediate-risk patients

MB Leon, CR Smith, MJ Mack, RR Makkar… - … England Journal of …, 2016 - Mass Medical Soc
Background Previous trials have shown that among high-risk patients with aortic stenosis,
survival rates are similar with transcatheter aortic-valve replacement (TAVR) and surgical …

[HTML][HTML] Two-year outcomes after transcatheter or surgical aortic-valve replacement

SK Kodali, MR Williams, CR Smith… - … England Journal of …, 2012 - Mass Medical Soc
Background The Placement of Aortic Transcatheter Valves (PARTNER) trial showed that
among high-risk patients with aortic stenosis, the 1-year survival rates are similar with …

Transcatheter aortic valve replacement versus surgical valve replacement in intermediate-risk patients: a propensity score analysis

VH Thourani, S Kodali, RR Makkar, HC Herrmann… - The Lancet, 2016 - thelancet.com
Background Transcatheter aortic valve replacement (TAVR) with the SAPIEN 3 valve
demonstrates good 30 day clinical outcomes in patients with severe aortic stenosis who are …

CT and MRI assessment of the aortic root and ascending aorta

LA Freeman, PM Young, TA Foley… - American Journal of …, 2013 - Am Roentgen Ray Soc
OBJECTIVE. We provide an outline of aortic anatomy and disease patterns, describe
methods of aortic measurement, and highlight measurement thresholds for surgical …

[HTML][HTML] Five-year outcomes of transcatheter or surgical aortic-valve replacement

RR Makkar, VH Thourani, MJ Mack… - … England Journal of …, 2020 - Mass Medical Soc
Background There are scant data on long-term clinical outcomes and bioprosthetic-valve
function after transcatheter aortic-valve replacement (TAVR) as compared with surgical …

Meta-analysis of the prognostic impact of stroke volume, gradient, and ejection fraction after transcatheter aortic valve implantation

MF Eleid, K Goel, MH Murad, PJ Erwin, RM Suri… - The American journal of …, 2015 - Elsevier
The prognostic implications of several baseline preprocedural variables in patients with
severe native valve aortic stenosis (AS) undergoing transcatheter aortic valve implantation …

Early clinical and echocardiographic outcomes after SAPIEN 3 transcatheter aortic valve replacement in inoperable, high-risk and intermediate-risk patients with aortic …

S Kodali, VH Thourani, J White… - European heart …, 2016 - academic.oup.com
Aims Based on randomized trials using first-generation devices, transcatheter aortic valve
replacement (TAVR) is well established in the treatment of high-risk (HR) patients with …

[HTML][HTML] The senescence-associated secretome as an indicator of age and medical risk

MJ Schafer, X Zhang, A Kumar, EJ Atkinson, YI Zhu… - JCI insight, 2020 - ncbi.nlm.nih.gov
Produced by senescent cells, the senescence-associated secretory phenotype (SASP) is a
potential driver of age-related dysfunction. We tested whether circulating concentrations of …

[PDF][PDF] Quantification of GDF11 and myostatin in human aging and cardiovascular disease

MJ Schafer, EJ Atkinson, PM Vanderboom, B Kotajarvi… - Cell metabolism, 2016 - cell.com
Growth and differentiation factor 11 (GDF11) is a transforming growth factor β superfamily
member with a controversial role in aging processes. We have developed a highly specific …