Left ventricular non-compaction cardiomyopathy
JA Towbin, A Lorts, JL Jefferies - The Lancet, 2015 - thelancet.com
Left ventricular non-compaction, the most recently classified form of cardiomyopathy, is
characterised by abnormal trabeculations in the left ventricle, most frequently at the apex. It …
characterised by abnormal trabeculations in the left ventricle, most frequently at the apex. It …
Cardiomyopathies due to left ventricular noncompaction, mitochondrial and storage diseases, and inborn errors of metabolism
JA Towbin, JL Jefferies - Circulation research, 2017 - Am Heart Assoc
The normal function of the human myocardium requires the proper generation and utilization
of energy and relies on a series of complex metabolic processes to achieve this normal …
of energy and relies on a series of complex metabolic processes to achieve this normal …
Dilated cardiomyopathy
JL Jefferies, JA Towbin - The Lancet, 2010 - thelancet.com
Dilated cardiomyopathy is characterised by left ventricular dilation that is associated with
systolic dysfunction. Diastolic dysfunction and impaired right ventricular function can …
systolic dysfunction. Diastolic dysfunction and impaired right ventricular function can …
Outcomes of restrictive cardiomyopathy in childhood and the influence of phenotype: a report from the Pediatric Cardiomyopathy Registry
SA Webber, SE Lipshultz, LA Sleeper, M Lu… - Circulation, 2012 - Am Heart Assoc
Background—Restrictive cardiomyopathy (RCM) has been associated with poor prognosis
in childhood. The goal of the present analysis was to use the Pediatric Cardiomyopathy …
in childhood. The goal of the present analysis was to use the Pediatric Cardiomyopathy …
Identification and functional characterization of NODAL rare variants in heterotaxy and isolated cardiovascular malformations
B Mohapatra, B Casey, H Li… - Human molecular …, 2009 - academic.oup.com
NODAL and its signaling pathway are known to play a key role in specification and
patterning of vertebrate embryos. Mutations in several genes encoding components of the …
patterning of vertebrate embryos. Mutations in several genes encoding components of the …
Early detection of acute kidney injury after pediatric cardiac surgery
JL Jefferies, P Devarajan - Progress in pediatric cardiology, 2016 - Elsevier
Acute kidney injury (AKI) is increasingly recognized as a common problem in children
undergoing cardiac surgery, with well documented increases in morbidity and mortality in …
undergoing cardiac surgery, with well documented increases in morbidity and mortality in …
Worsening renal function in children hospitalized with decompensated heart failure: evidence for a pediatric cardiorenal syndrome?
JF Price, AR Mott, HA Dickerson… - Pediatric Critical Care …, 2008 - journals.lww.com
Objectives: The purpose of this study was to determine the incidence of renal insufficiency in
children hospitalized with acute decompensated heart failure and whether worsening renal …
children hospitalized with acute decompensated heart failure and whether worsening renal …
Prevalence and progression of late gadolinium enhancement in children and adolescents with hypertrophic cardiomyopathy
A Axelsson Raja, H Farhad, AM Valente, JP Couce… - Circulation, 2018 - Am Heart Assoc
Background: Late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging
(CMR) is believed to represent dense replacement fibrosis. It is seen in≈ 60% of adult …
(CMR) is believed to represent dense replacement fibrosis. It is seen in≈ 60% of adult …
Association of race with disease expression and clinical outcomes among patients with hypertrophic cardiomyopathy
Importance Racial differences are recognized in multiple cardiovascular parameters,
including left ventricular hypertrophy and heart failure, which are 2 major manifestations of …
including left ventricular hypertrophy and heart failure, which are 2 major manifestations of …
[HTML][HTML] New genetic insights into congenital heart disease
SM Ware, JL Jefferies - Journal of clinical & experimental …, 2012 - ncbi.nlm.nih.gov
There has been remarkable progress in understanding the genetic basis of cardiovascular
malformations. Chromosome microarray analysis has provided a new tool to understand the …
malformations. Chromosome microarray analysis has provided a new tool to understand the …