[HTML][HTML] The lancet global health commission on global eye health: vision beyond 2020

MJ Burton, J Ramke, AP Marques… - The Lancet Global …, 2021 - thelancet.com
Eye health and vision have widespread and profound implications for many aspects of life,
health, sustainable development, and the economy. Yet nowadays, many people, families …

Mutation selection and the natural history of cancer

J Cairns - Nature, 1975 - nature.com
Survival of the rapidly renewing tissues of long-lived animals like man requires that they be
protected against the natural selection of fitter variant cells (that is the spontaneous …

The origin of human cancers

J Cairns - Nature, 1981 - nature.com
The limited evidence available suggests that most human cancers are not caused by
conventional mutagens but are more likely to be the result of genetic transpositions …

Evidence-based medicine: a new approach to teaching the practice of medicine

G Guyatt, J Cairns, D Churchill, D Cook, B Haynes… - Jama, 1992 - jamanetwork.com
A NEW paradigm for medical practice is emerging. Evidence-based medicine de-
emphasizes intuition, unsystematic clinical experience, and pathophysiologic rationale as …

Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre …

SS Jolly, S Yusuf, J Cairns, K Niemelä, D Xavier… - The Lancet, 2011 - thelancet.com
Background Small trials have suggested that radial access for percutaneous coronary
intervention (PCI) reduces vascular complications and bleeding compared with femoral …

Canadian atrial fibrillation anticoaguiation (CAFA) study

SJ Connolly, A Laupacis, M Gent, RS Roberts… - Journal of the American …, 1991 - Elsevier
Abstract The Canadian Atrial Fibrillation Anticoagulation Study was a randomized double-
blind placebo-controlled trial to assess the potential of warfarin to reduce systemic …

Aspirin, sulfinpyrazone, or both in unstable angina: results of a Canadian multicenter trial

JA Cairns, M Gent, J Singer, KJ Finnie… - … England Journal of …, 1985 - Mass Medical Soc
We performed a randomized, double-blind, placebo-controlled trial in 555 patients with
unstable angina who were hospitalized in coronary care units. Patients received one of four …

Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT

JA Cairns, SJ Connolly, R Roberts, M Gent - The Lancet, 1997 - thelancet.com
Background Survivors of acute myocardial infarction with frequent or repetitive ventricular
premature depolarisations (VPDs) have higher mortality 1–2 years after the event than those …

The origin of mutants

J Cairns, J Overbaugh, S Miller - Nature, 1988 - nature.com
Nucleic acids are replicated with conspicuous fidelity. Infrequently, however, they undergo
changes in sequence, and this process of change (mutation) generates the variability that …

[HTML][HTML] Smoking cessation support delivered via mobile phone text messaging (txt2stop): a single-blind, randomised trial

C Free, R Knight, S Robertson, R Whittaker, P Edwards… - The Lancet, 2011 - thelancet.com
Background Smoking cessation programmes delivered via mobile phone text messaging
show increases in self-reported quitting in the short term. We assessed the effect of an …