Anthracyclines are cytostatic antibiotics discovered almost half a century ago exerting their
action through inhibition of topoisomerase II. The two most representative drugs are …

Background: Alcoholic cardiomyopathy (ACM) is defined by a dilated and impaired left
ventricle due to chronic excess alcohol consumption. It is largely unknown which factors …

Background: The genetic cause of hypertrophic cardiomyopathy remains unexplained in a
substantial proportion of cases. Formin homology 2 domain containing 3 (FHOD3) may have …

Restrictive cardiomyopathy (RCM) is characterized by restrictive ventricular physiology in
the presence of normal diastolic volume and normal ventricular wall thickness (1). RCM is …

Background: The X-linked Danon disease manifests by severe cardiomyopathy, myopathy,
and neuropsychiatric problems. We designed this registry to generate a comprehensive …

Introduction The CRUSADE bleeding risk score (CBRS) accurately predicts major bleeding
in non-ST segment elevation myocardial infarction NSTEMI patients. However, little …

Introduction and objectives According to sudden cardiac death guidelines, an implantable
cardioverter-defibrillator (ICD) should be considered in patients with LMNA-related dilated …

Objective Up to 50% of patients with hypertrophic cardiomyopathy (HCM) show no disease-
causing variants in genetic studies. TRIM63 has been suggested as a candidate gene for …

Background Hereditary hemorrhagic telangiectasia (HHT) is a rare vascular disease with
autosomal dominant inheritance. Disease-causing variants in endoglin (ENG) and activin A …

Introduction and objectives Danon disease (DD) is caused by mutations in the LAMP2 gene.
It is considered a multisystemic disease characterized by hypertrophic cardiomyopathy with …