User profiles for "author:Jinho Heo"

Jinho Heo

University of Virginia
Verified email at virginia.edu
Cited by 449

Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis

J Heo, R Eki, T Abbas - Seminars in cancer biology, 2016 - Elsevier
F-box proteins are substrate receptors of the SCF (SKP1-Cullin 1-F-box protein) E3 ubiquitin
ligase that play important roles in a number of physiological processes and activities …

[HTML][HTML] A human short open reading frame (sORF)-encoded polypeptide that stimulates DNA end joining

SA Slavoff, J Heo, BA Budnik, LA Hanakahi… - Journal of Biological …, 2014 - ASBMB
The recent discovery of numerous human short open reading frame (sORF)-encoded
polypeptides (SEPs) has raised important questions about the functional roles of these …

Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations

BM Al-Barghouthi, WT Rosenow, KP Du, J Heo… - Elife, 2022 - elifesciences.org
Genome-wide association studies (GWASs) for bone mineral density (BMD) in humans have
identified over 1100 associations to date. However, identifying causal genes implicated by …

Growth of mycobacteria on carbon monoxide and methanol

SW Park, EH Hwang, H Park, JA Kim, J Heo… - Journal of …, 2003 - Am Soc Microbiol
Several mycobacterial strains, such as Mycobacterium flavescens, Mycobacterium gastri,
Mycobacterium neoaurum, Mycobacterium parafortuitum, Mycobacterium peregrinum …

TDP1 promotes assembly of non-homologous end joining protein complexes on DNA

J Heo, J Li, M Summerlin, A Hays, S Katyal… - DNA repair, 2015 - Elsevier
The repair of DNA double-strand breaks (DSB) is central to the maintenance of genomic
integrity. In tumor cells, the ability to repair DSBs predicts response to radiation and many …

[HTML][HTML] LMO7 deficiency reveals the significance of the cuticular plate for hearing function

TT Du, JB Dewey, EL Wagner, R Cui, J Heo… - Nature …, 2019 - nature.com
Sensory hair cells, the mechanoreceptors of the auditory and vestibular systems, harbor two
specialized elaborations of the apical surface, the hair bundle and the cuticular plate. In …

Selective toxicity of caffeic acid in hepatocellular carcinoma cells

DL Brautigan, M Gielata, J Heo, E Kubicka… - Biochemical and …, 2018 - Elsevier
Caffeic acid is a natural phytochemical structurally similar to other cinnamic acids. In this
study we found caffeic acid (CA) but not ferulic, sinapic or cinnamic acids inhibited …

Serial Circulating Tumor DNA Analysis with a Tumor-Naïve Next-Generation Sequencing Panel Detects Minimal Residual Disease and Predicts Outcome in Ovarian …

J Heo, YN Kim, S Shin, K Lee, JH Lee, YJ Lee, Z Choi… - Cancer Research, 2024 - AACR
Circulating tumor DNA (ctDNA) may aid in personalizing ovarian cancer therapeutic options.
Here, we aimed to assess the clinical utility of serial ctDNA testing using tumor-naïve, small …

[HTML][HTML] Polymorphisms within human cytomegalovirus chemokine (UL146/UL147) and cytokine receptor genes (UL144) are not predictive of sequelae in congenitally …

J Heo, S Petheram, G Demmler, JR Murph, SP Adler… - Virology, 2008 - Elsevier
Human cytomegalovirus (HCMV) viral chemokine, UL146, and TNF α-like receptor UL144
genes show a high degree of hypervariability in clinical isolates. These proteins are …

Novel human cytomegalovirus viral chemokines, vCXCL-1s, display functional selectivity for neutrophil signaling and function

J Heo, P Dogra, TJ Masi, EA Pitt, P de Kruijf… - The Journal of …, 2015 - journals.aai.org
Human CMV (HCMV) uses members of the hematopoietic system including neutrophils for
dissemination throughout the body. HCMV encodes a viral chemokine, vCXCL-1, that is …