User profiles for "author:James Crowley"

James J. Crowley, PhD

- Verified email at unc.edu - Cited by 22403

James Crowley

- Verified email at crowley-coutaz.fr - Cited by 16562

James L. Crowley

- Verified email at boisestate.edu - Cited by 15974

Active metal template synthesis of rotaxanes, catenanes and molecular shuttles

JD Crowley, SM Goldup, AL Lee, DA Leigh… - Chemical Society …, 2009 - pubs.rsc.org
Active metal template synthesis is a powerful new strategy for the construction of rotaxanes,
catenanes and other mechanically interlocked molecular structures. The key feature is that …

“Click-triazole” coordination chemistry: Exploiting 1, 4-disubstituted-1, 2, 3-triazoles as ligands

JD Crowley, DA McMorran - Click Triazoles, 2012 - Springer
Access to readily functionalized ligand architectures is of crucial importance in a range of
different areas including catalysis, metallopharmaceuticals, bioimaging …

Plešovice zircon—a new natural reference material for U–Pb and Hf isotopic microanalysis

J Sláma, J Košler, DJ Condon, JL Crowley, A Gerdes… - Chemical geology, 2008 - Elsevier
Matrix-matched calibration by natural zircon standards and analysis of natural materials as a
reference are the principle methods for achieving accurate results in microbeam U–Pb …

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

S Ripke, C O'dushlaine, K Chambert, JL Moran… - Nature …, 2013 - nature.com
Schizophrenia is an idiopathic mental disorder with a heritable component and a substantial
public health impact. We conducted a multi-stage genome-wide association study (GWAS) …

[PDF][PDF] Modeling linkage disequilibrium increases accuracy of polygenic risk scores

BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev… - The american journal of …, 2015 - cell.com
Polygenic risk scores have shown great promise in predicting complex disease risk and will
become more accurate as training sample sizes increase. The standard approach for …

Biochemical and physiological effects of sterol alterations in yeast—a review

LW Parks, SJ Smith, JH Crowley - Lipids, 1995 - Springer
Considerable progress has been made in the selection and characterization of mutants that
are defective in the synthesis of ergosterol in the yeast, Saccharomyces cerevisiae …

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

CR Marshall, DP Howrigan, D Merico… - Nature …, 2017 - nature.com
Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk …

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

HJ Watson, Z Yilmaz, LM Thornton, C Hübel… - Nature …, 2019 - nature.com
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness, affecting 0.9–4% of women and 0.3% of men,–, with twin-based heritability …

[PDF][PDF] Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

A Gusev, SH Lee, G Trynka, H Finucane… - The American Journal of …, 2014 - cell.com
Regulatory and coding variants are known to be enriched with associations identified by
genome-wide association studies (GWASs) of complex disease, but their contributions to …

Calibrating the end-Permian mass extinction

S Shen, JL Crowley, Y Wang, SA Bowring, DH Erwin… - science, 2011 - science.org
The end-Permian mass extinction was the most severe biodiversity crisis in Earth history. To
better constrain the timing, and ultimately the causes of this event, we collected a suite of …