User profiles for "author:Jakob Josiassen"

Jakob Josiassen

MD, PhD
Verified email at regionh.dk
Cited by 796

[HTML][HTML] Oxygen targets in comatose survivors of cardiac arrest

H Schmidt, J Kjaergaard, C Hassager… - … England Journal of …, 2022 - Mass Medical Soc
Background The appropriate oxygenation target for mechanical ventilation in comatose
survivors of out-of-hospital cardiac arrest is unknown. Methods In this randomized trial with a …

[HTML][HTML] Blood-pressure targets in comatose survivors of cardiac arrest

J Kjaergaard, JE Møller, H Schmidt… - … England Journal of …, 2022 - Mass Medical Soc
Background Evidence to support the choice of blood-pressure targets for the treatment of
comatose survivors of out-of-hospital cardiac arrest who are receiving intensive care is …

[HTML][HTML] Duration of device-based fever prevention after cardiac arrest

C Hassager, H Schmidt, JE Møller… - … England Journal of …, 2023 - Mass Medical Soc
Background Guidelines recommend active fever prevention for 72 hours after cardiac arrest.
Data from randomized clinical trials of this intervention have been lacking. Methods We …

Phenotyping cardiogenic shock

E Zweck, KL Thayer, OKL Helgestad… - Journal of the …, 2021 - Am Heart Assoc
Background Cardiogenic shock (CS) is a heterogeneous syndrome with varied
presentations and outcomes. We used a machine learning approach to test the hypothesis …

Treatment effects of interleukin-6 receptor antibodies for modulating the systemic inflammatory response after out-of-hospital cardiac arrest (The IMICA Trial) a double …

MAS Meyer, S Wiberg, J Grand, ASP Meyer… - Circulation, 2021 - Am Heart Assoc
Background: Patients experiencing out-of-hospital cardiac arrest who remain comatose after
initial resuscitation are at high risk of morbidity and mortality attributable to the ensuing post …

Temporal trends in incidence and patient characteristics in cardiogenic shock following acute myocardial infarction from 2010 to 2017: a Danish cohort study

OKL Helgestad, J Josiassen… - European journal of …, 2019 - Wiley Online Library
Aim We sought to describe the contemporary annual incidence of cardiogenic shock (CS)
following acute myocardial infarction (AMICS), the proportion of patients developing CS …

Contemporary trends in use of mechanical circulatory support in patients with acute MI and cardiogenic shock

OKL Helgestad, J Josiassen, C Hassager… - Open …, 2020 - openheart.bmj.com
Objectives To describe the contemporary trends in the use of mechanical circulatory support
(MCS) in patients with acute myocardial infarction and cardiogenic shock (AMICS). To …

Oral midodrine hydrochloride for prevention of orthostatic hypotension during early mobilization after hip arthroplasty: a randomized, double-blind, placebo-controlled …

Ø Jans, J Mehlsen, P Kjærsgaard-Andersen… - …, 2015 - pubs.asahq.org
Background Early postoperative mobilization is essential for rapid recovery but may be
impaired by orthostatic intolerance (OI) and orthostatic hypotension (OH), which are highly …

[HTML][HTML] Prehospital high-dose methylprednisolone in resuscitated out-of-hospital cardiac arrest patients (STEROHCA): a randomized clinical trial

LER Obling, RP Beske, MAS Meyer, J Grand… - Intensive Care …, 2023 - Springer
Purpose Patients who are successfully resuscitated following out-of-hospital cardiac arrest
(OHCA) are still at a high risk of neurological damage and death. Inflammation and brain …

Prognosis of myocardial infarction-related cardiogenic shock according to preadmission out-of-hospital cardiac arrest

MD Lauridsen, J Josiassen, M Schmidt, JH Butt… - Resuscitation, 2021 - Elsevier
Aims Out-of-hospital cardiac arrest (OHCA) is highly prevalent among patients with
myocardial infarction and cardiogenic shock (MI-CS). We aimed to examine the prognostic …