User profiles for "author:Jack V Tu"

Jack V Tu

Institute for Clinical Evaluative Sciences, Sunnybrook Health Sciences Centre, University of …
Verified email at ices.on.ca
Cited by 54525

Advantages and disadvantages of using artificial neural networks versus logistic regression for predicting medical outcomes

JV Tu - Journal of clinical epidemiology, 1996 - Elsevier
Artificial neural networks are algorithms that can be used to perform nonlinear statistical
modeling and provide a new alternative to logistic regression, the most commonly used …

Estimating the prevalence of heterozygous familial hypercholesterolaemia: a systematic review and meta-analysis

LE Akioyamen, J Genest, SD Shan, RL Reel… - BMJ open, 2017 - bmjopen.bmj.com
Objectives Heterozygous familial hypercholesterolaemia (FH) confers a significant risk for
premature cardiovascular disease (CVD). However, the estimated prevalence of FH varies …

A review of propensity-score methods and their use in cardiovascular research

S Deb, PC Austin, JV Tu, DT Ko, CD Mazer… - Canadian Journal of …, 2016 - Elsevier
Observational studies using propensity-score methods have been increasing in the
cardiovascular literature because randomized controlled trials are not always feasible or …

[HTML][HTML] Outcome of heart failure with preserved ejection fraction in a population-based study

RS Bhatia, JV Tu, DS Lee, PC Austin… - … England Journal of …, 2006 - Mass Medical Soc
Background The importance of heart failure with preserved ejection fraction is increasingly
recognized. We conducted a study to evaluate the epidemiologic features and outcomes of …

Predicting mortality among patients hospitalized for heart failure: derivation and validation of a clinical model

DS Lee, PC Austin, JL Rouleau, PP Liu, D Naimark… - Jama, 2003 - jamanetwork.com
ContextA predictive model of mortality in heart failure may be useful for clinicians to improve
communication with and care of hospitalized patients. ObjectivesTo identify predictors of …

Adherence with statin therapy in elderly patients with and without acute coronary syndromes

CA Jackevicius, M Mamdani, JV Tu - Jama, 2002 - jamanetwork.com
ContextLandmark clinical trials have demonstrated the survival benefits of statins, with
benefits usually starting after 1 to 2 years of treatment. Research prior to these trials of older …

[HTML][HTML] A population-based study of the drug interaction between proton pump inhibitors and clopidogrel

DN Juurlink, T Gomes, DT Ko, PE Szmitko, PC Austin… - Cmaj, 2009 - Can Med Assoc
Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active
metabolite. The clinical significance of this drug interaction is unknown. Methods: We …

Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: a population-based retrospective cohort …

GL Booth, MK Kapral, K Fung, JV Tu - The Lancet, 2006 - thelancet.com
Background Adults with diabetes are thought to have a high risk of cardiovascular disease
(CVD), irrespective of their age. The main aim of this study was to find out the age at which …

Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the framingham heart study of the national …

DS Lee, P Gona, RS Vasan, MG Larson, EJ Benjamin… - Circulation, 2009 - Am Heart Assoc
Background—The contributions of risk factors and disease pathogenesis to heart failure with
preserved ejection fraction (HFPEF) versus heart failure with reduced ejection fraction …

[HTML][HTML] Effects of socioeconomic status on access to invasive cardiac procedures and on mortality after acute myocardial infarction

DA Alter, CD Naylor, P Austin… - New England Journal of …, 1999 - Mass Medical Soc
Background Universal health care systems seek to ensure access to care on the basis of
need rather than income and to improve the health status of all citizens. We examined the …