Objective To review and appraise the validity and usefulness of published and preprint
reports of prediction models for prognosis of patients with covid-19, and for detecting people …

Chronic ischaemic mitral regurgitation (CIMR) remains one of the most complex and
unresolved aspects in the management of ischaemic heart disease. This review provides an …

Hypovolemia is frequent in patients with sepsis and may contribute to worse outcome. The
management of these patients is impeded by the low quality of the evidence for many of the …

Background Ischemic heart disease is a major cause of out-of-hospital cardiac arrest. The
role of immediate coronary angiography and percutaneous coronary intervention (PCI) in …

Objectives: The purposes of this study were to investigate whether, in patients with ST-
segment elevation myocardial infarction (STEMI) and multivessel disease (MVD) …

Objectives: In this study we considered the question of whether adjunction of glucose-insulin-
potassium (GIK) infusion to primary coronary transluminal angioplasty (PTCA) is effective in …

Background—In nondiabetic patients with ST-segment–elevation myocardial infarction,
acute hyperglycemia is associated with adverse outcome. Whether this association is due …

Background Severe COVID-19 is characterised by inflammation and coagulation in the
presence of complement system activation. We aimed to explore the potential benefit and …

Background Prophylaxis for gastrointestinal stress ulceration is frequently given to patients
in the intensive care unit (ICU), but its risks and benefits are unclear. Methods In this …

Metformin is the first choice drug for the treatment of patients with diabetes, but its use is
debated in patients with advanced cardiorenal disease. Epidemiological data suggest that …