Heart valve (HV) replacements are among the most widely used cardiovascular devices and
are in rising demand. Currently, clinically available devices are restricted to slightly modified …

The research field of auxetics, materials or structures exhibiting a negative Poisson's ratio,
has received attention because of the unusually advantageous material properties that can …

Valve replacement is the most common surgical treatment in patients with advanced valvular
heart disease. Mechanical and bio‐prostheses have been the traditional heart valve …

A novel nanocomposite polymer with a polycarbonate soft segment (PCU) and polyhedral
oligomeric silsesquioxanes (POSS) nanoparticle (POSS–PCU) has been selected for a …

During Atrial Fibrillation (AF) more than 90% of the left atrial thrombi responsible for
thromboembolic events originate in the left atrial appendage (LAA), a complex small sac …

Auxetic cellular tubes are emerging as potential candidates for a number of critical devices
requiring high resistance to kinking, such as angioplasty stents or annuloplasty rings. This …

Synthetic leaflet heart valves have been widely studied as possible alternatives to the
current mechanical and bioprosthetic valves. Assessing the in vitro hydrodynamic function of …

Calcification currently represents a major cause of failure of biological tissue heart valves. It
is a complex phenomenon influenced by a number of biochemical and mechanical factors …

Transcatheter aortic valve implantation (TAVI) can treat symptomatic patients with calcific
aortic stenosis. However, the severity and distribution of the calcification of valve leaflets can …

Mitral regurgitation is one of the most common forms of heart valve disorder, which may
result in heart failure. Due to the rapid ageing of the population, surgical repair and …