Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats

E Palojoki, A Saraste, A Eriksson… - American Journal …, 2001 - journals.physiology.org
We investigated the role of cardiomyocyte apoptosis in the remodeling of the left ventricle
from 24 h to 12 wk after myocardial infarction in the rat. Infarct size planimetry, quantification …

[HTML][HTML] Changes in the expression of nephrin gene and protein in experimental diabetic nephropathy

P Aaltonen, P Luimula, E Åström, T Palmen… - Laboratory …, 2001 - nature.com
Diabetic nephropathy is a major complication of diabetes leading to thickening of the
glomerular basement membrane, glomerular hypertrophy, mesangial expansion, and overt …

Drug-coated balloon for treatment of de-novo coronary artery lesions in patients with high bleeding risk (DEBUT): a single-blind, randomised, non-inferiority trial

TT Rissanen, S Uskela, J Eränen, P Mäntylä, A Olli… - The Lancet, 2019 - thelancet.com
Background The optimal technique of percutaneous coronary intervention in patients at high
bleeding risk is not known. The hypothesis of the DEBUT trial was that percutaneous …

Expression of heme oxygenase-1 in response to myocardial infarction in rats

P Lakkisto, E Palojoki, T Bäcklund, A Saraste… - Journal of molecular and …, 2002 - Elsevier
P. Lakkisto, E. Palojoki, T. Bäcklund, A. Saraste, I. Tikkanen, L.-M. Voipio-Pulkki and K.
Pulkki. Expression of Heme Oxygenase-1 in Response to Myocardial Infarction in Rats …

Clinical disease presentation and ECG characteristics of LMNA mutation carriers

L Ollila, K Nikus, M Holmström, M Jalanko… - Open …, 2017 - openheart.bmj.com
Objective Mutations in the LMNA gene encoding lamins A and C of the nuclear lamina are a
frequent cause of cardiomyopathy accounting for 5–8% of familial dilated cardiomyopathy …

Vasopeptidase inhibition has beneficial cardiac effects in spontaneously diabetic Goto–Kakizaki rats

T Grönholm, ZJ Cheng, E Palojoki, A Eriksson… - European journal of …, 2005 - Elsevier
In this study we examined diabetes-and hypertension-induced changes in cardiac structure
and function in an animal model of type 2 diabetes, the Goto–Kakizaki (GK) rat. We …

Effect of vasopeptidase inhibitor omapatrilat on cardiomyocyte apoptosis and ventricular remodeling in rat myocardial infarction

T Bäcklund, E Palojoki, A Saraste… - Cardiovascular …, 2003 - academic.oup.com
We have shown earlier that cardiomyocyte apoptosis continues at a high level late after
myocardial infarction and contributes to adverse cardiac remodeling. Here we studied …

Progesterone receptor in chicken bursa of Fabricius and thymus: evidence for expression in B-lymphocytes

S Pasanen, T Ylikomi, E Palojoki, H Syvälä… - Molecular and cellular …, 1998 - Elsevier
In the present work constitutive progesterone receptor (PR) expression in the chicken bursa
of Fabricius was detected in the stromal, smooth muscle and follicular medullary cells and …

Cardioprotective effects of vasopeptidase inhibition vs. angiotensin type 1-receptor blockade in spontaneously hypertensive rats on a high salt diet

T Gröholm, P Finckenberg, E Palojoki… - Hypertension …, 2004 - jstage.jst.go.jp
The aim of our study was to compare the cardioprotective effects of vasopeptidase inhibition
with those of angiotensin type 1 (AT1)-receptor blockade, a diuretic and the combination of …

Dual inhibition of angiotensin converting enzyme and neutral endopeptidase by omapatrilat in rat in vivo

T Bäcklund, E Palojoki, T Grönholm, A Eriksson… - Pharmacological …, 2001 - Elsevier
The pharmacological profile of a vasopeptidase inhibitor is dependent on the ratio of neutral
endopeptidase (NEP) vs angiotensin converting enzyme (ACE) inhibition of the particular …