Exercise testing in patients with asymptomatic moderate or severe aortic stenosis

S Saeed, R Rajani, R Seifert, D Parkin, JB Chambers - Heart, 2018 - heart.bmj.com
Objective To assess the safety and tolerability of treadmill exercise testing and the
association of revealed symptoms with outcome in apparently asymptomatic patients with …

[HTML][HTML] Bovine pericardial versus porcine stented replacement aortic valves: early results of a randomized comparison of the Perimount and the Mosaic valves

JB Chambers, R Rajani, D Parkin… - The Journal of Thoracic …, 2008 - Elsevier
OBJECTIVE: A stented bovine pericardial valve might be less obstructive than a stented
porcine valve. This study compared early hemodynamic function in a prospective series of …

Antihypertensive treatment with calcium channel blockers in patients with moderate or severe aortic stenosis: Relationship with all-cause mortality

S Saeed, G Mancia, R Rajani, D Parkin… - International journal of …, 2020 - Elsevier
Background Hypertension is common in patients with aortic stenosis (AS) and optimal blood
pressure (BP) control is advised to reduce arterial load and cardiovascular events. Whether …

Exercise treadmill testing in moderate or severe aortic stenosis: the left ventricular correlates of an exaggerated blood pressure rise

S Saeed, G Mancia, R Rajani, R Seifert… - Journal of the …, 2018 - Am Heart Assoc
Background Exaggerated blood pressure response during exercise predicts future
hypertension and cardiovascular events in general population and different patients groups …

A comparison of early redo surgery rates in Mosaic porcine and Perimount bovine pericardial valves

J Webb, D Parkin, K Tøndel, P Simitsis… - European Journal of …, 2018 - academic.oup.com
OBJECTIVES The objective of this study was to compare rates of redo surgery for the
Medtronic Mosaic 305 A Porcine Prosthesis and the Carpentier-Edwards Perimount …

Left atrial volume index predicts adverse events in asymptomatic moderate or severe aortic stenosis

S Saeed, R Rajani, M Tadic, D Parkin… - …, 2021 - Wiley Online Library
Objective In aortic stenosis (AS), chronic pressure overload on left ventricle (LV) leads to LV
hypertrophy, impaired relaxation, increased chamber stiffness, fibrosis and left atrial (LA) …

Rapid early rise in heart rate on treadmill exercise in patients with asymptomatic moderate or severe aortic stenosis: a new prognostic marker?

JB Chambers, R Rajani, D Parkin, S Saeed - Open Heart, 2019 - openheart.bmj.com
Objective To examine the clinical significance and prognostic value of an early rapid rise in
heart rate (RR-HR) in asymptomatic patients with moderate or severe aortic stenosis (AS) …

[HTML][HTML] Routine follow-up for patients with prosthetic valves: the value of a nurse-led valve clinic

D Parkin, JB Chambers - British Journal of Cardiology, 2012 - bjcardio.co.uk
Methods Guy's and St Thomas' Hospital Trust (GSTT) performs between 555 and 728 valve
operations annually, predominantly for patients within the South-East of England. Almost all …

Clinical significance and prognostic value of ST segment depression on ECG during exercise treadmill test in asymptomatic patients with moderate or severe aortic …

GMS Myrmel, D Wasim, R Rajani, D Parkin… - Scandinavian …, 2022 - Taylor & Francis
Objectives. In patients with asymptomatic moderate or severe aortic stenosis (AS), exercise
testing is used for evaluating the need for aortic valve intervention. Expert opinions about the …

Hypertension in aortic stenosis: relationship with revealed symptoms and functional measures on treadmill exercise

S Saeed, G Mancia, R Rajani, D Parkin… - Journal of …, 2019 - journals.lww.com
Background: The impact of hypertension on symptoms and functional capacity during
exercise treadmill test (ETT) in apparently asymptomatic patients with aortic stenosis is …