User profiles for "author:David Winlaw"
David WinlawCincinnati Children's Hospital Medical Center Verified email at cchmc.org Cited by 8939 |
[HTML][HTML] The health digital twin to tackle cardiovascular disease—a review of an emerging interdisciplinary field
G Coorey, GA Figtree, DF Fletcher, VJ Snelson… - NPJ digital …, 2022 - nature.com
Potential benefits of precision medicine in cardiovascular disease (CVD) include more
accurate phenotyping of individual patients with the same condition or presentation, using …
accurate phenotyping of individual patients with the same condition or presentation, using …
Congenital heart disease: current knowledge about causes and inheritance
Congenital heart disease: current knowledge about causes and inheritance | The Medical
Journal of Australia MJA Basic Search Advanced search search Use the Advanced search …
Journal of Australia MJA Basic Search Advanced search search Use the Advanced search …
European heart rhythm association (EHRA)/heart rhythm society (HRS)/Asia pacific heart rhythm society (APHRS)/latin American heart rhythm society (LAHRS) expert …
AAM Wilde, C Semsarian, MF Márquez, AS Shamloo… - Europace, 2022 - academic.oup.com
Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …
Redefining expectations of long-term survival after the Fontan procedure: twenty-five years of follow-up from the entire population of Australia and New Zealand
Y d'Udekem, AJ Iyengar, JC Galati, V Forsdick… - Circulation, 2014 - Am Heart Assoc
Background—The life expectancy of patients undergoing a Fontan procedure is unknown.
Methods and Results—Follow-up of all 1006 survivors of the 1089 patients who underwent a …
Methods and Results—Follow-up of all 1006 survivors of the 1089 patients who underwent a …
[PDF][PDF] Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and …
The T-box family transcription factor gene TBX20 acts in a conserved regulatory network,
guiding heart formation and patterning in diverse species. Mouse Tbx20 is expressed in …
guiding heart formation and patterning in diverse species. Mouse Tbx20 is expressed in …
[PDF][PDF] Contribution of global rare copy-number variants to the risk of sporadic congenital heart disease
Previous studies have shown that copy-number variants (CNVs) contribute to the risk of
complex developmental phenotypes. However, the contribution of global CNV burden to the …
complex developmental phenotypes. However, the contribution of global CNV burden to the …
[HTML][HTML] NAD deficiency, congenital malformations, and niacin supplementation
H Shi, A Enriquez, M Rapadas… - … England Journal of …, 2017 - Mass Medical Soc
Background Congenital malformations can be manifested as combinations of phenotypes
that co-occur more often than expected by chance. In many such cases, it has proved difficult …
that co-occur more often than expected by chance. In many such cases, it has proved difficult …
Increased nitric oxide production in heart failure
DS Winlaw, AM Keogh, CG Schyvens, PM Spratt… - The Lancet, 1994 - Elsevier
The role of nitric oxide in heart failure is unknown. The high-capacity inducible isoform of
nitric oxide synthase is present in the myocardium of patients with idiopathic dilated …
nitric oxide synthase is present in the myocardium of patients with idiopathic dilated …
A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells
The actin cytoskeleton is a potentially vulnerable property of cancer cells, yet
chemotherapeutic targeting attempts have been hampered by unacceptable toxicity. In this …
chemotherapeutic targeting attempts have been hampered by unacceptable toxicity. In this …
The Fontan epidemic: population projections from the Australia and New Zealand Fontan registry
C Schilling, K Dalziel, R Nunn, K Du Plessis… - International journal of …, 2016 - Elsevier
Background The number and age demographic of the future Fontan population is unknown.
Methods Population projections were calculated probabilistically using microsimulation …
Methods Population projections were calculated probabilistically using microsimulation …