Background Heart failure (HF) imposes both direct costs to healthcare systems and indirect
costs to society through morbidity, unpaid care costs, premature mortality and lost …

Objective To investigate the effects on cardiovascular outcomes of drug interventions that
increase high density lipoprotein levels. Design Meta-analysis. Studies reviewed …

Importance The comparative clinical efficacy of sodium-glucose cotransporter 2 (SGLT-2)
inhibitors, glucagon-like peptide 1 (GLP-1) agonists, and dipeptidyl peptidase 4 (DPP-4) …

Background Ischaemic heart disease (IHD) is the leading cause of death worldwide. The
World Health Organisation (WHO) collects mortality data coded using the International …

Background—Inflammatory immune activation is an important feature in chronic heart failure
(CHF). Little is known about the prognostic importance of tumor necrosis factor-α (TNF-α) …

Background Symptomatic relief is the primary goal of percutaneous coronary intervention
(PCI) in stable angina and is commonly observed clinically. However, there is no evidence …

Background—Although some patients with adult congenital heart disease (ACHD) report
limitations in exercise capacity, we hypothesized that depressed exercise capacity may be …

The European Society of Cardiology heart failure guidelines firmly recommend regular
physical activity and structured exercise training (ET), but this recommendation is still poorly …

Objectives: The purpose of this study was to develop an adenosine-independent, pressure-
derived index of coronary stenosis severity. Background: Assessment of stenosis severity …

Background—Serum uric acid (UA) could be a valid prognostic marker and useful for
metabolic, hemodynamic, and functional (MFH) staging in chronic heart failure (CHF) …