PET/CT imaging in cancer: current applications and future directions

MD Farwell, DA Pryma, DA Mankoff - Cancer, 2014 - Wiley Online Library
Positron emission tomography (PET) is a radiotracer imaging method that yields quantitative
images of regional in vivo biology and biochemistry. PET, now used in conjunction with …

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

C Twyman-Saint Victor, AJ Rech, A Maity, R Rengan… - Nature, 2015 - nature.com
Immune checkpoint inhibitors result in impressive clinical responses,,,, but optimal results
will require combination with each other and other therapies. This raises fundamental …

NANETS/SNMMI consensus statement on patient selection and appropriate use of 177Lu-DOTATATE peptide receptor radionuclide therapy

TA Hope, L Bodei, JA Chan, G El-Haddad… - Journal of Nuclear …, 2020 - Soc Nuclear Med
MATERIALS AND METHODS Systematic Review To inform the development of these
guidelines, a systematic review of evidence was performed. We followed the Preferred …

Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood–brain barrier divide

AM Chacko, C Li, DA Pryma, S Brem… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Brain tumors are inherently difficult to treat in large part due to the cellular blood–
brain barriers (BBBs) that limit the delivery of therapeutics to the tumor tissue from the …

Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric G250 (124I-cG250) and PET in patients with renal masses: a …

CR Divgi, N Pandit-Taskar, AA Jungbluth… - The lancet …, 2007 - thelancet.com
Background Preoperative identification of tumour type could have important implications for
the choice of treatment for renal cancers. Antibody cG250 reacts against carbonic anhydrase …

The nuclear receptor Rev-erbα controls circadian thermogenic plasticity

Z Gerhart-Hines, D Feng, MJ Emmett, LJ Everett… - Nature, 2013 - nature.com
Circadian oscillation of body temperature is a basic, evolutionarily conserved feature of
mammalian biology. In addition, homeostatic pathways allow organisms to protect their core …

Efficacy and safety of high-specific-activity 131I-MIBG therapy in patients with advanced pheochromocytoma or paraganglioma

DA Pryma, BB Chin, RB Noto, JS Dillon… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Patients with metastatic or unresectable (advanced) pheochromocytoma and
paraganglioma (PPGL) have poor prognoses and few treatment options. This multicenter …

Diagnostic accuracy and prognostic value of 18F-FDG PET in Hürthle cell thyroid cancer patients

DA Pryma, H Schöder, M Gönen… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Hürthle cell carcinoma is an uncommon and occasionally aggressive differentiated thyroid
cancer associated with increased mortality compared with other differentiated thyroid …

PennPET explorer: human imaging on a whole-body imager

AR Pantel, V Viswanath… - Journal of Nuclear …, 2020 - Soc Nuclear Med
The PennPET Explorer, a prototype whole-body imager currently operating with a 64-cm
axial field of view, can image the major body organs simultaneously with higher sensitivity …

The North American Neuroendocrine Tumor Society consensus guidelines for surveillance and management of metastatic and/or unresectable pheochromocytoma …

L Fishbein, J Del Rivero, T Else, JR Howe, SL Asa… - Pancreas, 2021 - journals.lww.com
This manuscript is the result of the North American Neuroendocrine Tumor Society
consensus conference on the medical management and surveillance of metastatic and …