Background: Very little is known about long-term valve durability after transcatheter aortic
valve replacement (TAVR). Objectives: This study sought to evaluate the incidence of …

Background: Clinical outcomes in large patient populations from real-world clinical practice
with a next-generation self-expanding transcatheter aortic valve are lacking. Objectives: This …

Objectives: This study sought to evaluate the effects of the Carillon device on mitral
regurgitation severity and left ventricular remodeling. Background: Functional mitral …

Many patients have iliofemoral vessel anatomy unsuitable for conventional transfemoral (TF)
transcatheter aortic valve implantation (TAVI). Safe and practical alternatives to the TF …

Objective To evaluate the impact of increased age on outcome from a strategy of early
invasive management and revascularisation in patients with acute coronary syndromes …

Acute coronary syndromes presenting with ST elevation are usually treated with emergency
reperfusion/revascularisation therapy. In contrast current evidence and national guidelines …

Background Cardiac adaptation to aortic stenosis (AS) appears to differ according to sex, but
reverse remodeling after aortic valve replacement has not been extensively described. The …

Testosterone is reported to have an acute vasodilating action in vitro, an effect that may
impart a favourable haemodynamic response in patients with chronic heart failure. However …

Aims There is some evidence to suggest that incompleteness of coronary artery
revascularisation after PCI is associated with inferior outcomes. The SYNTAX score was …

Background With expansion of transcatheter aortic valve implantation (TAVI) into younger
patients, valve durability is critically important. Aims We aimed to evaluate long‐term valve …