Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth
Mice carrying a hepatocyte-specific inactivation of the glucorticoid receptor (GR) gene show
a dramatic reduction in body size. Growth hormone signaling mediated by the Stat5 …
a dramatic reduction in body size. Growth hormone signaling mediated by the Stat5 …
A transcriptional network in polycystic kidney disease
L Gresh, E Fischer, A Reimann, M Tanguy… - The EMBO …, 2004 - embopress.org
Mutations in cystic kidney disease genes represent a major genetic cause of end‐stage
renal disease. However, the molecular cascades controlling the expression of these genes …
renal disease. However, the molecular cascades controlling the expression of these genes …
A versatile toolkit to produce sensitive FRET biosensors to visualize signaling in time and space
RD Fritz, M Letzelter, A Reimann, K Martin, L Fusco… - Science …, 2013 - science.org
Genetically encoded, ratiometric biosensors based on fluorescence resonance energy
transfer (FRET) are powerful tools to study the spatiotemporal dynamics of cell signaling …
transfer (FRET) are powerful tools to study the spatiotemporal dynamics of cell signaling …
Predictors of permanent pacemaker implantation after transcatheter aortic valve replacement with the SAPIEN 3
V Mauri, A Reimann, D Stern, M Scherner… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives: The aim of this study was to identify predictors of permanent pacemaker
implantation (PPMI) following transcatheter aortic valve replacement (TAVR) with a balloon …
implantation (PPMI) following transcatheter aortic valve replacement (TAVR) with a balloon …
Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno‐associated virus capsid and promoter
In this report, we describe the development of a modified adeno‐associated virus (AAV)
capsid and promoter for transduction of retinal ON‐bipolar cells. The bipolar cells, which are …
capsid and promoter for transduction of retinal ON‐bipolar cells. The bipolar cells, which are …
Report of the European Respiratory Society/European Cystic Fibrosis Society task force on the care of adults with cystic fibrosis
The improved survival in people with cystic fibrosis has led to an increasing number of
patients reaching adulthood. This trend is likely to be maintained over the next decades …
patients reaching adulthood. This trend is likely to be maintained over the next decades …
[HTML][HTML] Spatio-temporal co-ordination of RhoA, Rac1 and Cdc42 activation during prototypical edge protrusion and retraction dynamics
Abstract The three canonical Rho GTPases RhoA, Rac1 and Cdc42 co-ordinate cytoskeletal
dynamics. Recent studies indicate that all three Rho GTPases are activated at the leading …
dynamics. Recent studies indicate that all three Rho GTPases are activated at the leading …
Direct glucocorticoid receptor–Stat5 interaction in hepatocytes controls body size and maturation-related gene expression
D Engblom, JW Kornfeld, L Schwake… - Genes & …, 2007 - genesdev.cshlp.org
The glucocorticoid receptor regulates transcription through DNA binding as well as through
cross-talk with other transcription factors. In hepatocytes, the glucocorticoid receptor is …
cross-talk with other transcription factors. In hepatocytes, the glucocorticoid receptor is …
Repeated evolution of the pyrrolizidine alkaloid–mediated defense system in separate angiosperm lineages
A Reimann, N Nurhayati, A Backenkohler… - The Plant …, 2004 - academic.oup.com
Species of several unrelated families within the angiosperms are able to constitutively
produce pyrrolizidine alkaloids as a defense against herbivores. In pyrrolizidine alkaloid …
produce pyrrolizidine alkaloids as a defense against herbivores. In pyrrolizidine alkaloid …
[PDF][PDF] SrGAP2-dependent integration of membrane geometry and slit-robo-repulsive cues regulates fibroblast contact inhibition of locomotion
RD Fritz, D Menshykau, K Martin, A Reimann… - Developmental cell, 2015 - cell.com
Migrating fibroblasts undergo contact inhibition of locomotion (CIL), a process that was
discovered five decades ago and still is not fully understood at the molecular level. We …
discovered five decades ago and still is not fully understood at the molecular level. We …