Stem/progenitor cells derived from adult tissues: potential for the treatment of diabetes mellitus
A Lechner, JF Habener - American Journal of Physiology …, 2003 - journals.physiology.org
In view of the recent success in pancreatic islet transplantation, interest in treating diabetes
by the delivery of insulin-producing β-cells has been renewed. Because differentiated …
by the delivery of insulin-producing β-cells has been renewed. Because differentiated …
Mobile phone text-messaging interventions aimed to prevent cardiovascular diseases (Text2PreventCVD): systematic review and individual patient data meta-analysis
Background A variety of small mobile phone text-messaging interventions have indicated
improvement in risk factors for cardiovascular disease (CVD). Yet the extent of this …
improvement in risk factors for cardiovascular disease (CVD). Yet the extent of this …
No evidence for significant transdifferentiation of bone marrow into pancreatic β-cells in vivo
A Lechner, YG Yang, RA Blacken, L Wang… - Diabetes, 2004 - Am Diabetes Assoc
Several recent studies have suggested that the adult bone marrow harbors cells that can
differentiate into tissues from all three germ layers. Other reports have contradicted these …
differentiate into tissues from all three germ layers. Other reports have contradicted these …
[HTML][HTML] Targeted metabolomics identifies reliable and stable metabolites in human serum and plasma samples
M Breier, S Wahl, C Prehn, M Fugmann, U Ferrari… - PloS one, 2014 - journals.plos.org
Background Information regarding the variability of metabolite levels over time in an
individual is required to estimate the reproducibility of metabolite measurements. In …
individual is required to estimate the reproducibility of metabolite measurements. In …
Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 …
A Lechner, CA Leech, EJ Abraham, AL Nolan… - Biochemical and …, 2002 - Elsevier
The disease diabetes mellitus arises as a consequence of a failure of the β-cells in the islets
of Langerhans of the pancreas to produce insulin in the amounts required to meet the needs …
of Langerhans of the pancreas to produce insulin in the amounts required to meet the needs …
Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells
Objectives: Myeloid-derived suppressor cells (MDSCs) have been described as suppressors
of T-cell functions in many tumor models. However, MDSC in HIV-1 infection have not been …
of T-cell functions in many tumor models. However, MDSC in HIV-1 infection have not been …
[HTML][HTML] Diabetes knowledge and glycemic control among patients with type 2 diabetes in Bangladesh
Aims To explore the association between knowledge on diabetes and glycemic control
among patients with type 2 diabetes in Bangladesh. Methods A cross-sectional study was …
among patients with type 2 diabetes in Bangladesh. Methods A cross-sectional study was …
[HTML][HTML] The stool microbiota of insulin resistant women with recent gestational diabetes, a high risk group for type 2 diabetes
M Fugmann, M Breier, M Rottenkolber, F Banning… - Scientific reports, 2015 - nature.com
The gut microbiota has been linked to metabolic diseases. However, information on the
microbiome of young adults at risk for type 2 diabetes (T2D) is lacking. The aim of this cross …
microbiome of young adults at risk for type 2 diabetes (T2D) is lacking. The aim of this cross …
Different effects of lifestyle intervention in high-and low-risk prediabetes: results of the randomized controlled prediabetes lifestyle intervention study (PLIS)
Lifestyle intervention (LI) can prevent type 2 diabetes, but response to LI varies depending
on risk subphenotypes. We tested whether individuals with prediabetes with low risk (LR) …
on risk subphenotypes. We tested whether individuals with prediabetes with low risk (LR) …
Mechanisms of weight loss-induced remission in people with prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle …
A Sandforth, RJ von Schwartzenberg… - The Lancet Diabetes & …, 2023 - thelancet.com
Background Remission of type 2 diabetes can occur as a result of weight loss and is
characterised by liver fat and pancreas fat reduction and recovered insulin secretion. In this …
characterised by liver fat and pancreas fat reduction and recovered insulin secretion. In this …