Stem/progenitor cells derived from adult tissues: potential for the treatment of diabetes mellitus

A Lechner, JF Habener - American Journal of Physiology …, 2003 - journals.physiology.org
In view of the recent success in pancreatic islet transplantation, interest in treating diabetes
by the delivery of insulin-producing β-cells has been renewed. Because differentiated …

Mobile phone text-messaging interventions aimed to prevent cardiovascular diseases (Text2PreventCVD): systematic review and individual patient data meta-analysis

SMS Islam, AJ Farmer, K Bobrow, R Maddison… - Open …, 2019 - openheart.bmj.com
Background A variety of small mobile phone text-messaging interventions have indicated
improvement in risk factors for cardiovascular disease (CVD). Yet the extent of this …

No evidence for significant transdifferentiation of bone marrow into pancreatic β-cells in vivo

A Lechner, YG Yang, RA Blacken, L Wang… - Diabetes, 2004 - Am Diabetes Assoc
Several recent studies have suggested that the adult bone marrow harbors cells that can
differentiate into tissues from all three germ layers. Other reports have contradicted these …

[HTML][HTML] Targeted metabolomics identifies reliable and stable metabolites in human serum and plasma samples

M Breier, S Wahl, C Prehn, M Fugmann, U Ferrari… - PloS one, 2014 - journals.plos.org
Background Information regarding the variability of metabolite levels over time in an
individual is required to estimate the reproducibility of metabolite measurements. In …

Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 …

A Lechner, CA Leech, EJ Abraham, AL Nolan… - Biochemical and …, 2002 - Elsevier
The disease diabetes mellitus arises as a consequence of a failure of the β-cells in the islets
of Langerhans of the pancreas to produce insulin in the amounts required to meet the needs …

Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells

T Vollbrecht, R Stirner, A Tufman, J Roider, RM Huber… - Aids, 2012 - journals.lww.com
Objectives: Myeloid-derived suppressor cells (MDSCs) have been described as suppressors
of T-cell functions in many tumor models. However, MDSC in HIV-1 infection have not been …

[HTML][HTML] Diabetes knowledge and glycemic control among patients with type 2 diabetes in Bangladesh

SMS Islam, LW Niessen, J Seissler, U Ferrari, T Biswas… - SpringerPlus, 2015 - Springer
Aims To explore the association between knowledge on diabetes and glycemic control
among patients with type 2 diabetes in Bangladesh. Methods A cross-sectional study was …

[HTML][HTML] The stool microbiota of insulin resistant women with recent gestational diabetes, a high risk group for type 2 diabetes

M Fugmann, M Breier, M Rottenkolber, F Banning… - Scientific reports, 2015 - nature.com
The gut microbiota has been linked to metabolic diseases. However, information on the
microbiome of young adults at risk for type 2 diabetes (T2D) is lacking. The aim of this cross …

Different effects of lifestyle intervention in high-and low-risk prediabetes: results of the randomized controlled prediabetes lifestyle intervention study (PLIS)

A Fritsche, R Wagner, M Heni, K Kantartzis… - Diabetes, 2021 - Am Diabetes Assoc
Lifestyle intervention (LI) can prevent type 2 diabetes, but response to LI varies depending
on risk subphenotypes. We tested whether individuals with prediabetes with low risk (LR) …

Mechanisms of weight loss-induced remission in people with prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle …

A Sandforth, RJ von Schwartzenberg… - The Lancet Diabetes & …, 2023 - thelancet.com
Background Remission of type 2 diabetes can occur as a result of weight loss and is
characterised by liver fat and pancreas fat reduction and recovered insulin secretion. In this …