Thirty years ago, De Bold et al. reported that atrial extracts contain some biologically active
peptides, which promote a rapid and massive diuresis and natriuresis when injected in rats …

Both oxidative stress and inflammation are enhanced in chronic heart failure. Dysfunction of
cardiac mitochondria is a hallmark of heart failure and a leading cause of oxidative stress …

Interstitial pneumonia represents the most common cause of hospitalization for coronavirus
disease 2019 (COVID-19) and may be complicated by acute distress respiratory syndrome …

Objectives This study aimed to investigate the accuracy of a broad range of
echocardiographic variables to develop multiparametric scores to diagnose CA in patients …

Transthyretin (TTR) is a tetrameric protein synthesized mostly by the liver. As a result of gene
mutations or as an ageing-related phenomenon, TTR molecules may misfold and deposit in …

The aim of this review is to analyze in detail some possible pathophysiological mechanisms
linking obesity and cardiac endocrine function, in order to try to explain the negative …

Objectives: The aim of the present study was to investigate the prognostic significance of
chemosensitivity to hypercapnia in chronic heart failure (HF). Background: Increased …

Background: We compared the diagnostic accuracy of brain natriuretic peptide (BNP) and
amino-terminal proBNP (NT-proBNP) for diagnosis of preclinical and mild heart failure (HF) …

Increased chemosensitivity has been observed in HF (heart failure) and, in order to clarify its
pathophysiological and clinical relevance, the aim of the present study was to investigate its …

The increased analytical sensitivity of the new generation of methods for cardiac troponin I
(cTnI) and T (cTnT) has demonstrated that measurable troponin is present in the blood of …