Abstract
myo-Inositol, 500 mg twice a day, given to seven diabetic patients for two weeks, increased the amplitude of the evoked action potentials of the median, sural, and popliteal nerves by an average of 76%, 160%, and 40%, respectively. There was no significant change in the conduction velocities of these nerves, myo-Inositol may be valuable in the treatment of diabetic neuropathy.
MeSH terms
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Aged
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Clinical Trials as Topic
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Diabetes Mellitus / physiopathology*
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Diabetic Neuropathies / drug therapy*
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Dose-Response Relationship, Drug
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Double-Blind Method
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Drug Evaluation
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Evoked Potentials / drug effects
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Humans
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Inositol / administration & dosage
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Inositol / pharmacology*
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Inositol / therapeutic use
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Lumbosacral Plexus / physiopathology
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Median Nerve / physiopathology
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Middle Aged
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Neural Conduction / drug effects
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Peripheral Nerves / drug effects*
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Peripheral Nerves / physiopathology
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Placebos
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Sural Nerve / physiopathology