Only a minority of patients referred for elective coronary artery bypass surgery have risk factors diagnosed and treated according to established guidelines

Diab Vasc Dis Res. 2007 Jun;4(2):112-6. doi: 10.3132/dvdr.2007.028.

Abstract

Patients deserve to be medically optimised for treatment of metabolic risk factors and hypertension before referral for elective coronary artery bypass grafting (CABG). We describe here a prospective study of 347 consecutive patients referred for elective CABG. An oral glucose tolerance test (OGTT) was performed and metabolic risk factors and hypertension were determined pre-operatively. Compliance to treatment guidelines was calculated. From the total of 347 patients, 80 patients (23%) had known and 66 (19%) had previously unknown diabetes. Dysglycaemia (that is, diabetes and pre-diabetes) was found in 194 (73%) of the 267 patients without known diabetes. Among patients with dysglycaemia, 111/274 (41%) received one antihypertensive medication, or none, and blood pressure guidelines were met in 39/274 (14%); statins were being taken by 206 (75%; average dose 23 mg simvastatin) and low-density lipoprotein (LDL)-cholesterol guidelines were met in 43 (16%). In conclusion, diabetes diagnosis and titration of risk factor treatment to guidelines is inadequate even in elective CABG patients. A pre-admission OGTT affords an opportunity to improve care significantly.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Aged
  • Antihypertensive Agents / pharmacology
  • Antihypertensive Agents / therapeutic use*
  • Blood Glucose
  • Blood Pressure / drug effects
  • Coronary Artery Bypass*
  • Coronary Artery Disease / blood
  • Coronary Artery Disease / drug therapy
  • Coronary Artery Disease / etiology
  • Coronary Artery Disease / physiopathology
  • Coronary Artery Disease / surgery*
  • Diabetes Mellitus / blood
  • Diabetes Mellitus / diagnosis*
  • Diabetes Mellitus / drug therapy
  • Diabetes Mellitus / epidemiology
  • Dyslipidemias / blood
  • Dyslipidemias / complications
  • Dyslipidemias / drug therapy*
  • Elective Surgical Procedures
  • Female
  • Glucose Tolerance Test
  • Guideline Adherence
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
  • Hypertension / complications
  • Hypertension / drug therapy*
  • Hypertension / physiopathology
  • Incidence
  • Lipids / blood
  • Male
  • Middle Aged
  • Practice Guidelines as Topic
  • Prospective Studies
  • Referral and Consultation*
  • Risk Factors
  • Sweden / epidemiology

Substances

  • Antihypertensive Agents
  • Blood Glucose
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Lipids