Chest
Conduction System in Children with Acquired Immunodeficiency Syndrome
Section snippets
MATERIALS AND METHODS
All six children were diagnosed to have AIDS and treated at Children's Hospital, Newark, NJ, where they died. There were four females and two males, and the ages ranged from seven months to seven years. All children were born to IV drug-addicted mothers and/or fathers, and some of the parents had AIDS and died of this disease. Antibody titers against human immunodeficiency virus (HIV) were measured by an enzyme-linked immunosorbent assay and confirmed by Western blot techniques. Each case
FINDINGS*
The findings in the conduction system and the entire heart are given in Table 2, Table 3.
The term myocarditis, as used in this article, implies an infiltration of mononuclear cells, with or without necrosis of the myocytes. This agrees with the terminology of Roldan et al.19 It does not agree with the terminology of Reilly et al,23 Anderson et al,24 and Baroldi et al,25 who follow Aretz et al31 in calling a condition myocarditis only when, in addition to the infiltration of inflammatory cells,
DISCUSSION
The pathologic findings in the cases of AIDS in adults12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25 (with the exception of the heart) are (a) meningitis, (b) encephalitis, (c) pneumonitis, (d) lymphoid depletion, (e) esophagitis, (f) oral pathology, (g) herpes simplex, (h) Kaposi's sarcoma, and (i) malignant lymphoma. The organisms involved in the secondary causation of these entities are Pneumocystis, Toxoplasma, Cytomegalovirus, Cryptococcus, Aspergillus, Nocardia, Candida,
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Aided by grant HL 30558-06 from the National Institutes of Health, National Heart Lung and Blood Institute, Bethesda, MD.