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The effect of late preterm birth on mortality of infants with major congenital heart defects

Journal of Perinatology volume 32, pages 51–54 (2012)Cite this article

Abstract

Objective:

We evaluated the effect of late preterm delivery (34 to 36 weeks) on hospital mortality of infants with congenital heart defects (CHDs).

Study Design:

Retrospective record review of infants with major CHD born at or after to 34 weeks, cared for in a single tertiary perinatal center between 2002 and 2009. Factors associated with death before discharge from the hospital were ascertained using univariate and multivariate analyses.

Result:

Of the 753 infants with CHD, 117 were born at late preterm. Using logistic regression analysis, white race (OR; 95% CI) (0.60; 0.39 to 0.95), late preterm delivery (2.70; 1.69 to 4.33), and need for intubation in the delivery room (3.15; 1.92 to 5.17) were independently associated with hospital death.

Conclusion:

Late preterm birth of infants with major CHDs was independently associated with increased risk of hospital death compared with delivery at more mature gestational ages.

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Authors and Affiliations

  1. Department of Pediatrics and Communicable Diseases,

    A W Swenson, R E Schumacher & M A Attar

  2. University of Michigan Health System, Ann Arbor, MI, USA

    A W Swenson, R E Schumacher & M A Attar

  3. Department of Critical Care Support Services, University of Michigan Health System, Ann Arbor, MI, USA

    R E Dechert

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  1. A W Swenson
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  2. R E Dechert
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  3. R E Schumacher
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  4. M A Attar
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Correspondence to M A Attar.

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Swenson, A., Dechert, R., Schumacher, R. et al. The effect of late preterm birth on mortality of infants with major congenital heart defects. J Perinatol 32, 51–54 (2012). https://doi.org/10.1038/jp.2011.50

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  • DOI: https://doi.org/10.1038/jp.2011.50

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