Renal transplantationCandidateFactors Associated With Peak Oxygen Uptake in Hemodialysis Patients Awaiting Renal Transplantation
Section snippets
Patients and Methods
Thirty patients with chronic renal failure who were undergoing hemodialysis and waiting for renal transplantation included 14 women and 16 men of overall mean age of 40.2 ± 10.3 years and a duration of dialysis of 133.1 ± 63.3 months. The study was approved by the local ethics committee, and all patients provided informed consent. No patient had signs or symptoms of active infection or inflammation. We excluded individuals who had clinically evident malnutrition, malignancy, or a chronic
Results
The most common causes of ESRD were vesicoureteral reflux and nephrolithiasis, which were present in 10 (33.4%) of the patients included in the study. The cause of ESRD was glomerulonephritis in 8 patients (26.7%), hypertension in 4 (13.3%), polycystic kidney disease in 3 (10.0%), amyloidosis in 1 (3.3%), and unknown in 4 (13.3%).
Table 1 shows the PFT and CPET results, the MIS, and the biochemical parameters of the 30 hemodialysis patients. The MIS was negatively correlated with the peak Vo2 (r
Discussion
In our study, we observed that, among hemodialysis patients awaiting renal transplantation, exercise capacity reflected by the peak Vo2 was negatively correlated with the MIS. Peak Vo2 was positively correlated with the serum triglyceride level and negatively with the serum ferritin level. The results of a multiple linear regression analysis showed that only the MIS was independently correlated with the peak Vo2 in hemodialysis patients awaiting renal transplantation.
The low peak Vo2 in chronic
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Impact of Resistance Training on Factors Involved in the Development of New-Onset Diabetes After Transplantation in Renal Transplant Recipients: An Open Randomized Pilot Study
2016, Canadian Journal of DiabetesCitation Excerpt :In addition, as observed in type 2 diabetes, insulin resistance and decreased insulin secretion favour the development of NODAT (7). Patients with chronic kidney failure demonstrate limitations in exercise capacity secondary to muscle weakness (8–12). There is also impairment in cardiorespiratory fitness levels related to peripheral muscle dysfunction (13,14).
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