Original articleAdult cardiacRisk of Valve-Related Events After Aortic Valve Repair
Section snippets
Patient Population and Follow-Up
This study was approved by the institutional review board, and the need for individual informed consent was waived. Between 1995 and 2010, 475 patients underwent elective AV repair for aortic insufficiency (AI) or aortic root aneurysm. Patient demographics and operative data were collected prospectively in our institutional database and analyzed retrospectively. Clinical follow-up was conducted through either outpatient visits or telephone follow-up. Information on survival status,
Patient Characteristics, Short-Term Outcomes, and Survival
Patient characteristics are summarized in Table 1. The mean age was 53 years, and the majority of patients were male with normal left ventricular function. Aortic valve morphology was bicuspid in 34% of patients, and 58% had significant preoperative AI. Operative techniques and characteristics are displayed in Table 2. Aortic leaflet repair was performed in 71% of the patients, and an annuloplasty technique was used in 95%. Aortic valve-sparing root replacement was performed in 49% of repairs,
Comment
This study demonstrates that AV repair can be performed to treat multiple types of AV and aortic root disease with good mid-term survival, freedom from reoperation, and freedom from valve-related events. Specifically, at 10 years there was overall survival of 73% ± 5%, freedom from valve-related death of 90% ± 3%, freedom from significant AI of 84% ± 3 %, freedom from AV reoperation of 86 ± 3%, and freedom from valve-related events including AV reoperation, thromboembolic event, bleeding, and
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