Original articlePediatric cardiacCurrent Expectations for Surgical Repair of Isolated Ventricular Septal Defects
Section snippets
Patient Population
The Texas Children's Hospital Congenital Heart Surgery Database was queried for patients 18 years of age or younger undergoing VSD repair between January 1, 2000, and December 31, 2006. The medical records of these patients were retrospectively reviewed after approval by the Baylor College of Medicine Institutional Review Board on February 2, 2007. Given the retrospective nature of the study, permission was given for waiver of consent.
Patients undergoing isolated VSD repair were extracted from
Patient Demographics
The median age at repair was 10 months (range, 20 days to 18 years) and weight was 7 kg (range, 2 to 66 kg). For the subgroup of patients with genetic abnormalities, the median age was 6.1 months (range, 37 days to 7.5 years) and the median weight was 5.4 kg (range, 2.4 to 25.7 kg), compared with nonsyndromic patients whose median age was 14.5 months (range, 20 days to 17.8 years) and median weight was 9.1 kg (range, 3.0 to 65.8 kg). The probability values for both age and weight of syndromic
Comment
Results for surgical repair of ventricular septal defects have evolved significantly since the first series of direct vision closure reported by Lillehei and colleagues in 1955 [3]. Advances in surgical technique and intraoperative and perioperative management have led to marked improvement in outcomes for these patients. Long-term survival and clinical outcomes for these patients are excellent, with one recent study citing 92% of patients in New York Heart Association class I more than 20
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