Original articleCardiovascularAttentional Dysfunction in Children After Corrective Cardiac Surgery in Infancy
Section snippets
Patient Population
The study was approved by the Ethical Medical Committee of the Aachen University of Technology, and written informed consent of the parents was obtained.
The study group comprised a total of 40 unselected children, divided into two subgroups. Group A consisted of 20 patients with TOF (age at corrective surgery 0.7 ± 0 .3 years, age at evaluation 7.4 ± 1.4 years). Group B consisted of 20 patients with VSD (age at corrective surgery 0 .7 ± 0.2 years, age at evaluation 7.4 ± 1.9 years).
Attentional Functions Compared With Healthy Controls and Between TOF and VSD Patients
Group comparisons among the three groups (TOF, VSD, controls) including IQ as covariate revealed a significant group effect only for the conflict system whereas the two other attentional networks (alerting and orienting) as well as the mean reaction time and mean accuracy did not differ between the groups (Table 2). Pairwise analysis of covariance showed a significantly reduced conflict performance in the TOF group when compared with the control group (p = 0.005) as well as with the VSD group (p
Comment
Corrective surgical procedures for cardiac defects in infancy should carry the chance for a life that might differ less from that of healthy children compared with patients who undergo surgical intervention at a later age. On the other hand, current understanding of mid- and long-term neurology and development of the operated-on children considers multiple, mostly interrelated preoperative, perioperative, and postoperative risk factors that may adversely affect the central nervous system
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