Original articleCardiovascularAortic Valve Replacement in Octogenarians: Risk Factors for Early and Late Mortality
Section snippets
Material and Methods
This retrospective study was approved by the Institutional Review Board of Washington University School of Medicine, and individual consent was waived. Between November 1, 1993, and December 31, 2005, 245 patients aged 80 years or older underwent AVR with or without concomitant CABG. Preoperative demographic information and perioperative events were stored in a computerized database. New York Heart Association (NYHA) functional class was assessed preoperatively for each patient.
Members of the
Study Population Demographics
Men and women were equally represented (Table 1). The mean age of the patients was 83.6 ± 2.9 years (range, 80 to 92 years), and 94% (230/245) were white. Ten percent of patients had previous cardiac surgery, 66% had a history of hypertension, and 18% had diabetes mellitus. Peripheral vascular disease and chronic renal insufficiency were less common. Five patients (2%) were in an immunocompromised state, and 19 (8%) were in chronic renal insufficiency (one was on hemodialysis).
The most common
Comment
These results demonstrate that good late outcomes may be achieved with AVR in patients aged 80 years or older regardless of NYHA functional status. Late survival rates postoperatively showed that more than half of patients were still alive at 5 years. Similar 5-year survival rates of 55% to 66% have been achieved at other centers [1, 2, 3, 4, 5, 7, 9, 10, 11]. Even though operative mortality was higher than our results in the younger population, this slight increase was not prohibitive.
Such
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