ReviewMeta-Analysis of Predictors of All-Cause Mortality After Transcatheter Aortic Valve Implantation
Section snippets
Methods
This study was conducted in accordance with the current guidelines, including the recent Preferred Reporting Items for Systematic reviews and Meta-Analyses amendment to the Quality of Reporting of Meta-analyses statement, and recommendations from The Cochrane Collaboration and Meta-analysis Of Observational Studies in Epidemiology (MOOSE).10
PubMed and Cochrane databases were searched for reports published in English from January 2002 to June 2013 according to the following highly sensitive
Results
The search strategy yielded 1,088 reports. Four reports derived from congresses were added, resulting in a total of 1,092 citations. All citations were first screened at title and abstract level; the 31 remaining reports were subsequently screened full text. Of the full-text analyzed citations, 4 were excluded because of reporting duplicate data11, 12, 13, 14 and 2 because of the absence of data on independent predictors for adverse events.15, 16 Twenty-five studies were finally included in
Discussion
Profound understanding of factors determining patient survival after TAVI is of paramount importance in clinical practice not only to enable to accurately select patients, that is, only those in whom treatment benefit outweighs the risk, but also to take appropriate measures to prevent complications in high-risk subjects, especially considering that the commonly used logistic EuroSCORE falls short in predicting mortality, as it does not take account of periprocedural events, and it is known to
Disclosures
The authors have no conflicts of interest to disclose.
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