Systemic HypertensionTwo- and Three-Dimensional Speckle Tracking Analysis of the Relation Between Myocardial Deformation and Functional Capacity in Patients With Systemic Hypertension
Section snippets
Methods
Our cross-sectional study included 101 consecutive untreated subjects who were referred to our outpatient clinic due to hypertension screening, and 101 treated hypertensive patients who were referred to our clinic because of treatment evaluation. The study was conducted at Cardiology Department, University Hospital “Dr Dragisa Misovic” in Belgrade, Serbia from October 2011 to March 2013. All the participants underwent 24-hour blood pressure (BP) monitoring, and according to 24-hour systolic BP
Results
Demographic and clinical parameters of the study population are presented in Table 1. The participants were of similar age and gender distribution. The prevalence of different antihypertensive drug groups was similar between the well-controlled and uncontrolled groups.
All participants had similar LV diameters, whereas LV relative wall thickness, left atrial diameter, 2D LV mass index, and E/e′ ratio progressively and significantly increased from the control group, across the well-controlled and
Discussion
The present study explored LV mechanics, assessed by 2D and 3D speckle tracking imaging, and functional capacity in the hypertensive population: the recently diagnosed untreated hypertensive patients and the treated hypertensive patients with well-controlled arterial hypertension and with uncontrolled hypertension; and compared with the normotensive controls. Our results revealed several interesting findings: (1) 2D assessment of LV mechanics showed that only longitudinal and, partly,
Disclosures
The authors have no conflicts of interest to disclose.
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Drs. Celic and Tadic contributed equally to this work.
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