Coronary artery diseaseRelation of Body Fat Categories by Gallagher Classification and by Continuous Variables to Mortality in Patients With Coronary Heart Disease
Section snippets
Methods
We retrospectively reviewed the records of 622 consecutive patients with stable CHD who were referred for potential entry into phase 2 cardiac rehabilitation and exercise programs from January 1, 2000 to July 31, 2005, who had baseline anthropometric, lipid, and clinical data, as we have previously described6, 7, 8, 9 (41 patients were excluded because of incomplete data). The subjects were referred after coronary artery bypass graft surgery (33%), myocardial infarctions (21%), and/or a
Results
Baseline characteristics of the subject population and of the 4 distinct Gallagher BF groups are listed in Table 2, which demonstrates that our population was overall overweight or obese as determined by either BMI or BF. The groups differed in age, peak oxygen consumption, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and fasting glucose. The underweight group contained significantly more women, and underweight patients more often had histories of hypertension and
Discussion
These data confirm the presence of an obesity paradox using subcutaneous BF in a cohort of patients with CHD. For the first time, this obesity paradox was demonstrated using the Gallagher classification of BF, with highest mortality noted in the underweight and normal-BF groups and the lowest mortality in the overweight group.
Numerous studies have demonstrated that once cardiovascular (CV) diseases, including CHD, become established, the overweight and obese seem to have a better prognosis than
Disclosures
The authors have no conflicts of interest to disclose.
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