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Aortic valve sclerosis relates to cardiovascular events in patients with hypertension (a LIFE substudy)

https://doi.org/10.1016/j.amjcard.2004.08.080Get rights and content

This study investigated whether aortic valve (AV) sclerosis was associated with traditional cardiovascular (CV) risk factors and CV events in hypertensive patients with electrocardiographic left ventricular (LV) hypertrophy, as previously demonstrated in the general population. AV sclerosis was associated with several CV risk factors and predicted CV events independently of prevalent CV disease and traditional CV risk factors, including LV mass and ejection fraction.

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Acknowledgment

We thank Mary Paranicas, BA, Shonna Cohen, BA, and Andreas Moan, MD, for their invaluable assistance with study coordination. Furthermore, we would like to thank the LIFE echocardiographic study investigators: Denmark: Jens Berning (Ålborg), Per Hildebrandt (Frederiksberg), John Larsen (Næstved), OleLederballe Pedersen (Viborg), Jens Rokkedal (Glostrup), Kristian Wachtell (Glostrup); Finland: Tapio Aalto (Helsinki), Erik Engblom (Turku), Markku S. Nieminen (Helsinki), Antti Ylitalo (Oulu);

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This study was supported in part by grants from Merck & Co., Inc., West Point, Pennsylvania.

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