Effect of caffeine administered intravenously on intracoronary-administered adenosine-induced coronary hemodynamics in patients with coronary artery disease

https://doi.org/10.1016/j.amjcard.2003.10.017Get rights and content

Abstract

It is believed that caffeine attenuates the coronary hyperemic response to adenosine by blocking the A2a receptors. We studied the effect of caffeine on adenosine-induced myocardial hyperemia measured by fractional flow reserve after intracoronary adenosine administration. Fractional flow reserve was not affected by intravenous caffeine infusion at a dose that was comparable to oral consumption.

Section snippets

Acknowledgements

We thank Edmond Brown, RN, Linda Lowe, CRNP, Linda Turner, RN, Mittie Williams, RT, Florence Henderson, CV tech, and Earl Moore, RT, for their assistance in the present study.

References (21)

There are more references available in the full text version of this article.

Cited by (46)

View all citing articles on Scopus
View full text