Lipid oxidation products in ischemic porcine heart tissue
References (54)
- et al.
Phytochemistry
(1976) - et al.
Methods Enzymol.
(1990) - et al.
Arch. Biochem. Biophys.
(1962) Free Radic. Biol. Med.
(1990)- et al.
FEBS Lett.
(1981) - et al.
BBA
(1994) - et al.
Anal. Biochem.
(1992) - et al.
Anal. Biochem.
(1986) - et al.
Anal. Biochem.
(1991) - et al.
Chem. Phys. Lipids
(1995)
J. Biol. Chem.
Biochem. Biophys. Res. Commun.
Chem. Phys. Lipids
Arzneim.-Forsch.
Int. J. Tissue React.
Aldehydes in Biological Systems: Their Natural Occurence and Biological Activities
Chem.-Biol. Interact.
Chem. Phys. Lipids
Chem. Phys. Lipids
Can. J. Biochem. Physiol.
Lipids
Lipids
Eur. J. Biochem.
Chem. Phys. Lipids
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2013, Prostaglandins and Other Lipid MediatorsCitation Excerpt :In addition, sEH null mice have been demonstrated to have significantly higher EpOME:DiHOME ratios and are protected against I/R injury suggesting that DiHOMEs can be detrimental to the heart [10]. In experimental models of myocardial ischemia, DiHOME levels rise from 1–3 μg/g of tissue to 4–22 μg/g of tissue [39]. DiHOMEs but not EpOME depress Na+ channels, K+ channels and trigger mitochondrial dysfunction [36,40,41].
Glycolate and 2-phosphoglycolate content of tissues measured by ion chromatography coupled to mass spectrometry
2012, Analytical BiochemistryCitation Excerpt :A small amount of glyoxal is produced in cells from the peroxidation that occurs as a result of normal metabolism [3–5]. Some glycolate may also be produced by the reduction of glyoxylate by glyoxylate reductase (GRHPR), particularly in tissues that metabolize hydroxyproline such as the liver and kidney [1]. Our results with cultured hepatocytes have shown that there is a metabolic pathway from fructose to glycolate that is believed to arise from glycolaldehyde production, but in vivo studies with human subjects indicated that ingesting fructose in amounts up to 21% of the calories did not alter glycolate excretion, suggesting this pathway is minor [26].
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