Macroemboli and microemboli during cardiopulmonary bypass

https://doi.org/10.1016/0003-4975(95)00105-TGet rights and content

Macroscopic and microscopic emboli of gas, biologic aggregates, and inorganic debris can occur during cardiac operations with cardiopulmonary bypass and may result in end-organ ischemia. In the current era pump-generated embolism is a diminishing cause of perioperative neurologic injury, which now appears to be related mostly to atheroembolism from manipulation of the atherosclerotic ascending aorta, and presents a continuing technical challenge to the surgeon.

References (33)

  • OsbornJJ et al.

    Clinical use of a Dacron wool filter during perfusion for open heart surgery

    J Thorac Cardiovasc Surg

    (1970)
  • AshmorePG et al.

    The incidence and effects of particulate aggregation and microembolism in pump-oxygenator systems

    J Thorac Cardiovasc Surg

    (1968)
  • WareingTH et al.

    Management of the severely atherosclerotic ascending aorta during cardiac operations: a strategy for detection and treatment

    J Thorac Cardiovasc Surg

    (1992)
  • PadayacheeTS et al.

    The effect of arterial filtration on reduction of gaseous microemboli in the middle cerebral artery during cardiopulmonary bypass

    Ann Thorac Surg

    (1988)
  • FaichneyA et al.

    Prostacyclin in cardiopulmonary bypass operations

    J Thorac Cardiovasc Surg

    (1982)
  • RichardsonPD

    Qualitative and quantitative methods for investigating gas emboli in blood

    Med Instrum

    (1985)
  • Cited by (0)

    Presented at the Conference on CNS Dysfunction After Cardiac Surgery: Defining the Problem, Fort Lauderdale, FL, Dec 10–11, 1994.

    View full text