Clinical study
Problems in echocardiographic volume determinations: Echocardiographic-angiographic correlations in the presence or absence of asynergy

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Abstract

The relation of minor and major axes of the left ventricle was determined in 100 left ventriculograms performed in the right anterior oblique projection. This relation taken over a wide range of volumes was used to derive a theoretically correct equation for determination of ventricular volume by echocardiography. The final equation was: V = [7.0/2.4 + D] (D3), where V = volume and D = the echocardiographically measured internal dimension. In 12 patients without asynergy, this equation accurately and directly calculated end-systolic and enddiastolic volumes whether the left ventricle was small or large. However, in 12 patients exhibiting left ventricular asynergy the correlation between angiographically and echocardiographically determined volumes was poor. Thus, caution is recommended in the use of time-motion echocardiography to calculate ventricular volumes in patients with coronary artery disease and possible left ventricular asynergy.

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This study was supported by Training Grant ITI 5679 and Program Project Grant PO1 11306 from the U. S. Public Health Service, Bethesda, Md.

Present address: Division of Cardiology and Department of Medicine, Mount Sinai Hospital and Mount Sinai School of Medicine of the City University of New York, New York, N. Y.

Present address: Cardiac Catheterization Laboratory and Department of Medicine, Temple University Health Sciences Center, Philadelphia, Pa.

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